[摘要] 目的 分析曲美他嗪治療冠心病伴心力衰竭臨床治療效果。方法 方便抽取2018年6月—2019年6月在該院接受治療急性心肌梗死患者78例為研究對(duì)象,根據(jù)其住院先后順序從1~78編號(hào),再按等差數(shù)列首項(xiàng)為1,公差為2的方式將78例患者平均分為兩組,即對(duì)照組與實(shí)驗(yàn)組,兩組患者均為39例。對(duì)照組患者行常規(guī)治療,實(shí)驗(yàn)組在常規(guī)治療基礎(chǔ)上予以曲美他嗪治療,對(duì)比兩組患者治療效果和患者血流情況。結(jié)果 實(shí)驗(yàn)組患者治療總有效率(97.43%)高于對(duì)照組(79.48%)(χ2=6.210,P<0.05);實(shí)驗(yàn)組患者左室射血分?jǐn)?shù)(LVEF)、左室舒張末期內(nèi)徑 (LVEDD) 和左心室縮短分?jǐn)?shù) (FS)分別為(44.61±5.34)%、(52.36±6.98)mm、(32.81±7.64)%,對(duì)照組患者左室射血分?jǐn)?shù)(LVEF)、左室舒張末期內(nèi)徑 (LVEDD) 和左心室縮短分?jǐn)?shù) (FS)分別為(34.68±5.39)%、(58.21±5.34)mm、(25.36±5.94)%,差異有統(tǒng)計(jì)學(xué)意義(t=10.375、5.397、5.364,P<0.05)。 結(jié)論 曲美他嗪治療冠心病伴心力衰竭效果優(yōu)于常規(guī)治療,能夠提高治療總有效率,提高患者左室射血分?jǐn)?shù)(LVEF)和左心室縮短分?jǐn)?shù) (FS),使患者左室舒張末期內(nèi)徑處于正常水平。
[關(guān)鍵詞] 曲美他嗪;冠心病;心力衰竭;治療效果;血流情況
[中圖分類號(hào)] R541? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-0742(2020)08(a)-0107-03
Clinical Analysis of Trimetazidine in the Treatment of Coronary Heart Disease with Heart Failure
GAO Li-li
Department of Cardiology, Lingcheng People's Hospital, Dezhou, Shandong Province, 253500 China
[Abstract] Objective To analyze the clinical effect of trimetazidine in the treatment of coronary heart disease with heart failure. Methods Seventy-eight patients with acute myocardial infarction who were treated in the hospital from June 2018 to June 2019 were conveniently selected as the research subjects. They were numbered from 1-78 according to the order of their hospitalization, and then the first item in the arithmetic sequence was 1 and the tolerance was 2, the 78 patients were divided into two groups, namely the control group and the experimental group, with 39 patients in both groups. Patients in the control group received conventional treatment, while experimental group was treated with trimetazidine on the basis of routine care. The treatment effect and blood flow of patients in the two groups were compared. Results The total effective rate of treatment in the experimental group (97.43%) was higher than that in the control group (79.48%)(χ2=6.210, P<0.05); patients in the experimental group had left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDD), left ventricular shortening fraction (FS) was (44.61±5.34)%, (52.36±6.98)mm, and (32.81±7.64)%. Patients in the control group had left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter(LVEDD) and left ventricular shortening fraction (FS) were (34.68±5.39)%, (58.21±5.34)mm, (25.36±5.94)%,the difference was statistically significant (t=10.375, 5.397, 5.364, P<0.05). Conclusion Trimetazidine is more effective than conventional treatment for coronary heart disease with heart failure. It can improve the total effective rate of treatment, increase the left ventricular ejection fraction (LVEF) and left ventricular shortening fraction (FS), and make the patient's left ventricular end-diastole. The neck is at a normal level.
綜上所述,曲美他嗪治療冠心病伴心力衰竭效果優(yōu)于常規(guī)治療,能夠提高治療總有效率,提高患者左室射血分?jǐn)?shù)(LVEF)和左心室縮短分?jǐn)?shù) (FS),使患者左室舒張末期內(nèi)徑處于正常水平,值得在臨床上推廣。
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(收稿日期:2020-05-09)
[作者簡(jiǎn)介] 高麗麗(1983-),女,山東德州人,本科,主治醫(yī)師,研究方向:心內(nèi)科。