河南某醫(yī)院108例嗜麥芽窄食單胞菌臨床分布及耐藥分析

邱衛(wèi)強

doi：10.3969/j.issn.1007-614x.2014.9.2

摘 要 目的：了解嗜麥芽窄食單胞菌的臨床分布特點及耐藥情況，為臨床診斷嗜麥芽窄食單胞菌感染并及時合理選擇抗生素提供實驗室依據(jù)。方法：根據(jù)臨床和實驗室操作規(guī)程對醫(yī)院分離的108份陽性標(biāo)本進行實驗室鑒定及K-B藥敏試驗，統(tǒng)計其臨床分布及藥物敏感結(jié)果。結(jié)果：嗜麥芽窄食單胞菌主要感染人群為老年人和青少年，臨床分布以呼吸科、ICU、新生兒科為主，標(biāo)本主要來自于痰液，細(xì)菌最敏感的藥物是頭孢哌酮/舒巴坦、復(fù)方新諾明和左氧氟沙星、哌拉西林/他唑巴坦，對亞胺培南、氨基糖苷類及大部分β內(nèi)酰胺類抗菌藥物呈高度耐藥。結(jié)論：嗜麥芽窄食單胞菌耐藥情況十分嚴(yán)重，要盡快建立該菌在醫(yī)院的耐藥譜，加強耐藥監(jiān)測，根據(jù)藥敏試驗，合理規(guī)范使用抗菌藥物。

關(guān)鍵詞 嗜麥芽窄食單胞菌 藥敏試驗 臨床分析

Clinical distribution and drug resistance analysis of 108 patients with maltophilia Aeromonas in a hospital of Henan province

Qiu Weiqiang

Inspection department in Zhumadian Central Hospital of Henan province，450000

Abstract Objective：To observe maltophilia aeromonas clinical distribution and drug resistance，in order to provide laboratory basis of maltophilia Aeromonas infections clinical diagnosis and choice an reasonable antibiotics treatment timely.Methods：108 positive samples separation in 2012～2013 were taken to laboratory identification and KB susceptibility testing based on clinical and laboratory procedures，statistic clinical distribution and drug sensitivity.Results：Maltophilia aeromonas mainly infection of the elderly and youth populations， clinical distributed mainly in the respiratory department，ICU and neonatology，Specimen mainly from the sputum，cefoperazone/Shuba Tan，cotrimoxazole and levofloxacin，piperacillin/tazobactam are the most sensitive bacterial drugs，imipenem，aminoglycosides and mostly of βlactam antimicrobial agents were highly resistant.Conclusion：Maltophilia aeromonas have very serious durg resistant.To create a resistance spectrum in the hospital as soon as possible，strengthen the resistance monitoring，use of antimicrobial drugs reasonable and standard based on susceptibility testing.

Key words Maltophilia Aeromonas；Susceptibility testing；Clinical analysis

doi：10.3969/j.issn.1007-614x.2014.9.2

摘 要 目的：了解嗜麥芽窄食單胞菌的臨床分布特點及耐藥情況，為臨床診斷嗜麥芽窄食單胞菌感染并及時合理選擇抗生素提供實驗室依據(jù)。方法：根據(jù)臨床和實驗室操作規(guī)程對醫(yī)院分離的108份陽性標(biāo)本進行實驗室鑒定及K-B藥敏試驗，統(tǒng)計其臨床分布及藥物敏感結(jié)果。結(jié)果：嗜麥芽窄食單胞菌主要感染人群為老年人和青少年，臨床分布以呼吸科、ICU、新生兒科為主，標(biāo)本主要來自于痰液，細(xì)菌最敏感的藥物是頭孢哌酮/舒巴坦、復(fù)方新諾明和左氧氟沙星、哌拉西林/他唑巴坦，對亞胺培南、氨基糖苷類及大部分β內(nèi)酰胺類抗菌藥物呈高度耐藥。結(jié)論：嗜麥芽窄食單胞菌耐藥情況十分嚴(yán)重，要盡快建立該菌在醫(yī)院的耐藥譜，加強耐藥監(jiān)測，根據(jù)藥敏試驗，合理規(guī)范使用抗菌藥物。

關(guān)鍵詞 嗜麥芽窄食單胞菌 藥敏試驗 臨床分析

Clinical distribution and drug resistance analysis of 108 patients with maltophilia Aeromonas in a hospital of Henan province

Qiu Weiqiang

Inspection department in Zhumadian Central Hospital of Henan province，450000

Abstract Objective：To observe maltophilia aeromonas clinical distribution and drug resistance，in order to provide laboratory basis of maltophilia Aeromonas infections clinical diagnosis and choice an reasonable antibiotics treatment timely.Methods：108 positive samples separation in 2012～2013 were taken to laboratory identification and KB susceptibility testing based on clinical and laboratory procedures，statistic clinical distribution and drug sensitivity.Results：Maltophilia aeromonas mainly infection of the elderly and youth populations， clinical distributed mainly in the respiratory department，ICU and neonatology，Specimen mainly from the sputum，cefoperazone/Shuba Tan，cotrimoxazole and levofloxacin，piperacillin/tazobactam are the most sensitive bacterial drugs，imipenem，aminoglycosides and mostly of βlactam antimicrobial agents were highly resistant.Conclusion：Maltophilia aeromonas have very serious durg resistant.To create a resistance spectrum in the hospital as soon as possible，strengthen the resistance monitoring，use of antimicrobial drugs reasonable and standard based on susceptibility testing.

Key words Maltophilia Aeromonas；Susceptibility testing；Clinical analysis

doi：10.3969/j.issn.1007-614x.2014.9.2

摘 要 目的：了解嗜麥芽窄食單胞菌的臨床分布特點及耐藥情況，為臨床診斷嗜麥芽窄食單胞菌感染并及時合理選擇抗生素提供實驗室依據(jù)。方法：根據(jù)臨床和實驗室操作規(guī)程對醫(yī)院分離的108份陽性標(biāo)本進行實驗室鑒定及K-B藥敏試驗，統(tǒng)計其臨床分布及藥物敏感結(jié)果。結(jié)果：嗜麥芽窄食單胞菌主要感染人群為老年人和青少年，臨床分布以呼吸科、ICU、新生兒科為主，標(biāo)本主要來自于痰液，細(xì)菌最敏感的藥物是頭孢哌酮/舒巴坦、復(fù)方新諾明和左氧氟沙星、哌拉西林/他唑巴坦，對亞胺培南、氨基糖苷類及大部分β內(nèi)酰胺類抗菌藥物呈高度耐藥。結(jié)論：嗜麥芽窄食單胞菌耐藥情況十分嚴(yán)重，要盡快建立該菌在醫(yī)院的耐藥譜，加強耐藥監(jiān)測，根據(jù)藥敏試驗，合理規(guī)范使用抗菌藥物。

關(guān)鍵詞 嗜麥芽窄食單胞菌 藥敏試驗 臨床分析

Clinical distribution and drug resistance analysis of 108 patients with maltophilia Aeromonas in a hospital of Henan province

Qiu Weiqiang

Inspection department in Zhumadian Central Hospital of Henan province，450000

Abstract Objective：To observe maltophilia aeromonas clinical distribution and drug resistance，in order to provide laboratory basis of maltophilia Aeromonas infections clinical diagnosis and choice an reasonable antibiotics treatment timely.Methods：108 positive samples separation in 2012～2013 were taken to laboratory identification and KB susceptibility testing based on clinical and laboratory procedures，statistic clinical distribution and drug sensitivity.Results：Maltophilia aeromonas mainly infection of the elderly and youth populations， clinical distributed mainly in the respiratory department，ICU and neonatology，Specimen mainly from the sputum，cefoperazone/Shuba Tan，cotrimoxazole and levofloxacin，piperacillin/tazobactam are the most sensitive bacterial drugs，imipenem，aminoglycosides and mostly of βlactam antimicrobial agents were highly resistant.Conclusion：Maltophilia aeromonas have very serious durg resistant.To create a resistance spectrum in the hospital as soon as possible，strengthen the resistance monitoring，use of antimicrobial drugs reasonable and standard based on susceptibility testing.

Key words Maltophilia Aeromonas；Susceptibility testing；Clinical analysis

doi：10.3969/j.issn.1007-614x.2014.9.2

摘 要 目的：了解嗜麥芽窄食單胞菌的臨床分布特點及耐藥情況，為臨床診斷嗜麥芽窄食單胞菌感染并及時合理選擇抗生素提供實驗室依據(jù)。方法：根據(jù)臨床和實驗室操作規(guī)程對醫(yī)院分離的108份陽性標(biāo)本進行實驗室鑒定及K-B藥敏試驗，統(tǒng)計其臨床分布及藥物敏感結(jié)果。結(jié)果：嗜麥芽窄食單胞菌主要感染人群為老年人和青少年，臨床分布以呼吸科、ICU、新生兒科為主，標(biāo)本主要來自于痰液，細(xì)菌最敏感的藥物是頭孢哌酮/舒巴坦、復(fù)方新諾明和左氧氟沙星、哌拉西林/他唑巴坦，對亞胺培南、氨基糖苷類及大部分β內(nèi)酰胺類抗菌藥物呈高度耐藥。結(jié)論：嗜麥芽窄食單胞菌耐藥情況十分嚴(yán)重，要盡快建立該菌在醫(yī)院的耐藥譜，加強耐藥監(jiān)測，根據(jù)藥敏試驗，合理規(guī)范使用抗菌藥物。

關(guān)鍵詞 嗜麥芽窄食單胞菌 藥敏試驗 臨床分析

Clinical distribution and drug resistance analysis of 108 patients with maltophilia Aeromonas in a hospital of Henan province

Qiu Weiqiang

Inspection department in Zhumadian Central Hospital of Henan province，450000

Abstract Objective：To observe maltophilia aeromonas clinical distribution and drug resistance，in order to provide laboratory basis of maltophilia Aeromonas infections clinical diagnosis and choice an reasonable antibiotics treatment timely.Methods：108 positive samples separation in 2012～2013 were taken to laboratory identification and KB susceptibility testing based on clinical and laboratory procedures，statistic clinical distribution and drug sensitivity.Results：Maltophilia aeromonas mainly infection of the elderly and youth populations， clinical distributed mainly in the respiratory department，ICU and neonatology，Specimen mainly from the sputum，cefoperazone/Shuba Tan，cotrimoxazole and levofloxacin，piperacillin/tazobactam are the most sensitive bacterial drugs，imipenem，aminoglycosides and mostly of βlactam antimicrobial agents were highly resistant.Conclusion：Maltophilia aeromonas have very serious durg resistant.To create a resistance spectrum in the hospital as soon as possible，strengthen the resistance monitoring，use of antimicrobial drugs reasonable and standard based on susceptibility testing.

Key words Maltophilia Aeromonas；Susceptibility testing；Clinical analysis

doi：10.3969/j.issn.1007-614x.2014.9.2

摘 要 目的：了解嗜麥芽窄食單胞菌的臨床分布特點及耐藥情況，為臨床診斷嗜麥芽窄食單胞菌感染并及時合理選擇抗生素提供實驗室依據(jù)。方法：根據(jù)臨床和實驗室操作規(guī)程對醫(yī)院分離的108份陽性標(biāo)本進行實驗室鑒定及K-B藥敏試驗，統(tǒng)計其臨床分布及藥物敏感結(jié)果。結(jié)果：嗜麥芽窄食單胞菌主要感染人群為老年人和青少年，臨床分布以呼吸科、ICU、新生兒科為主，標(biāo)本主要來自于痰液，細(xì)菌最敏感的藥物是頭孢哌酮/舒巴坦、復(fù)方新諾明和左氧氟沙星、哌拉西林/他唑巴坦，對亞胺培南、氨基糖苷類及大部分β內(nèi)酰胺類抗菌藥物呈高度耐藥。結(jié)論：嗜麥芽窄食單胞菌耐藥情況十分嚴(yán)重，要盡快建立該菌在醫(yī)院的耐藥譜，加強耐藥監(jiān)測，根據(jù)藥敏試驗，合理規(guī)范使用抗菌藥物。

關(guān)鍵詞 嗜麥芽窄食單胞菌 藥敏試驗 臨床分析

Clinical distribution and drug resistance analysis of 108 patients with maltophilia Aeromonas in a hospital of Henan province

Qiu Weiqiang

Inspection department in Zhumadian Central Hospital of Henan province，450000

Abstract Objective：To observe maltophilia aeromonas clinical distribution and drug resistance，in order to provide laboratory basis of maltophilia Aeromonas infections clinical diagnosis and choice an reasonable antibiotics treatment timely.Methods：108 positive samples separation in 2012～2013 were taken to laboratory identification and KB susceptibility testing based on clinical and laboratory procedures，statistic clinical distribution and drug sensitivity.Results：Maltophilia aeromonas mainly infection of the elderly and youth populations， clinical distributed mainly in the respiratory department，ICU and neonatology，Specimen mainly from the sputum，cefoperazone/Shuba Tan，cotrimoxazole and levofloxacin，piperacillin/tazobactam are the most sensitive bacterial drugs，imipenem，aminoglycosides and mostly of βlactam antimicrobial agents were highly resistant.Conclusion：Maltophilia aeromonas have very serious durg resistant.To create a resistance spectrum in the hospital as soon as possible，strengthen the resistance monitoring，use of antimicrobial drugs reasonable and standard based on susceptibility testing.

Key words Maltophilia Aeromonas；Susceptibility testing；Clinical analysis

doi：10.3969/j.issn.1007-614x.2014.9.2

摘 要 目的：了解嗜麥芽窄食單胞菌的臨床分布特點及耐藥情況，為臨床診斷嗜麥芽窄食單胞菌感染并及時合理選擇抗生素提供實驗室依據(jù)。方法：根據(jù)臨床和實驗室操作規(guī)程對醫(yī)院分離的108份陽性標(biāo)本進行實驗室鑒定及K-B藥敏試驗，統(tǒng)計其臨床分布及藥物敏感結(jié)果。結(jié)果：嗜麥芽窄食單胞菌主要感染人群為老年人和青少年，臨床分布以呼吸科、ICU、新生兒科為主，標(biāo)本主要來自于痰液，細(xì)菌最敏感的藥物是頭孢哌酮/舒巴坦、復(fù)方新諾明和左氧氟沙星、哌拉西林/他唑巴坦，對亞胺培南、氨基糖苷類及大部分β內(nèi)酰胺類抗菌藥物呈高度耐藥。結(jié)論：嗜麥芽窄食單胞菌耐藥情況十分嚴(yán)重，要盡快建立該菌在醫(yī)院的耐藥譜，加強耐藥監(jiān)測，根據(jù)藥敏試驗，合理規(guī)范使用抗菌藥物。

關(guān)鍵詞 嗜麥芽窄食單胞菌 藥敏試驗 臨床分析

Clinical distribution and drug resistance analysis of 108 patients with maltophilia Aeromonas in a hospital of Henan province

Qiu Weiqiang

Inspection department in Zhumadian Central Hospital of Henan province，450000

Abstract Objective：To observe maltophilia aeromonas clinical distribution and drug resistance，in order to provide laboratory basis of maltophilia Aeromonas infections clinical diagnosis and choice an reasonable antibiotics treatment timely.Methods：108 positive samples separation in 2012～2013 were taken to laboratory identification and KB susceptibility testing based on clinical and laboratory procedures，statistic clinical distribution and drug sensitivity.Results：Maltophilia aeromonas mainly infection of the elderly and youth populations， clinical distributed mainly in the respiratory department，ICU and neonatology，Specimen mainly from the sputum，cefoperazone/Shuba Tan，cotrimoxazole and levofloxacin，piperacillin/tazobactam are the most sensitive bacterial drugs，imipenem，aminoglycosides and mostly of βlactam antimicrobial agents were highly resistant.Conclusion：Maltophilia aeromonas have very serious durg resistant.To create a resistance spectrum in the hospital as soon as possible，strengthen the resistance monitoring，use of antimicrobial drugs reasonable and standard based on susceptibility testing.

Key words Maltophilia Aeromonas；Susceptibility testing；Clinical analysis