葉大彬 宋文信 孫鳳
[摘要] 目的 觀察不同預(yù)后的冠心病心力衰竭患者經(jīng)皮冠脈介入術(shù)(PCI)術(shù)前動態(tài)心電圖特征,分析動態(tài)心電圖特征與預(yù)后的關(guān)系。 方法 回顧性分析2018年1月—2019年1月在重慶醫(yī)科大學附屬大足醫(yī)院完成PCI治療并在術(shù)后完成1年隨訪的80例冠心病心力衰竭患者的臨床資料。所有患者均于PCI術(shù)前接受動態(tài)心電圖檢查,根據(jù)隨訪期間有無不良心血管事件發(fā)生分為預(yù)后良好組(69例)、預(yù)后不良組(11例)。比較不同預(yù)后冠心病心力衰竭患者的基線資料及術(shù)前動態(tài)心電圖特征,繪制受試者操作特征(ROC)曲線,分析術(shù)前心電圖特征,預(yù)測冠心病心力衰竭患者PCI術(shù)后不良預(yù)后的價值。 結(jié)果 冠心病心力衰竭患者不良心血管事件發(fā)生率為13.75%(11/80);預(yù)后不良組的全程全部NN間期標準差(SDNN)、24 h內(nèi)每5分鐘NN間期均值的標準差(SDANN)、24 h內(nèi)每5分鐘一般正常RR期間的標準差平均值(SDNNI)、全程相鄰NN間期之差的均方根值(rMSSD)值均低于預(yù)后良好組,差異有統(tǒng)計學意義(P < 0.05)。SDNN、SDANN、SDNNI、rMSSD預(yù)測冠心病心力衰竭患者PCI術(shù)后預(yù)后不良的曲線下面積(AUC)分別為0.865、0.920、0.848、0.918,預(yù)測價值較理想,且SDANN、rMSSD預(yù)測價值更好。結(jié)論 冠心病心力衰竭患者可通過PCI術(shù)前檢測SDNN、SDANN、SDNNI、rMSSD等心率變異性時域指標預(yù)測預(yù)后,盡早給予合理化干預(yù),改善預(yù)后。
[關(guān)鍵詞] 冠心病;心力衰竭;經(jīng)皮冠脈介入術(shù);動態(tài)心電圖;不良心血管事件
[中圖分類號] R541.6 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1673-7210(2020)08(b)-0049-04
[Abstract] Objective To observe the characteristics of preoperative percutaneous coronary intervention (PCI) dynamic electrocardiogram characteristics in patients with coronary artery heart disease and heart failure with different prognosis and to analyze the relationship between preoperative PCI dynamic electrocardiogram and prognosis. Methods The clinical data of 80 patients with coronary artery heart disease and heart failure who were treated in Dazu Hospital Affiliated to Chongqing Medical University from January 2018 to January 2019, completed PCI treatment and one year follow-up after treatment, was retrospectively analyzed. All patients received dynamic electocardiogram detection before PCI, according to whether the patients had adverse cardiovascular events during the one year follow-up period, they were divided into good prognosis group (69 cases) and poor prognosis group (11 cases). The baseline data and preoperative dynamic electrocardiogram characteristics of patients with coronary artery heart disease and heart failure with different prognostic outcomes were compared, then the receiver operating characteristic (ROC) curve was drew to analyze the value of preoperative dynamic electrocardiogram characteristics in predicting the poor prognosis of patients with coronary artery heart disease and heart failure after PCI. Results The incidence of adverse cardiovascular events in patients with coronary artery heart disease and heart failure was 13.75% (11/80); the standard deviation of NN intervals (SDNN), standard deviation average of NN intervals (SDANN), standard deviation of normal RR intervals index (SDNNI), root mean square of successive differences (rMSSD) in the poor prognosis group were lower than those in the good prognosis group, the differences were statistically significant (P < 0.05). The ROC curve was drew to obtain SDNN, SDANN, SDNNI and rMSSD to predict the poor prognosis of patients with coronary artery heart disease and heart failure after PCI, the area under the curve (AUC) were 0.865, 0.920, 0.848 and 0.918 separately, and the predictive value was ideal. The prediction values of SDANN and rMSSD were better. Conclusion Patients with coronary artery heart disease and heart failure can predict the prognosis by SDNN, SDANN, SDNNI, rMSSD and other heart rate variability time domain indicators before PCI, to give reasonable intervention as soon as possible to improve the prognosis.
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(收稿日期:2020-05-07)