王耀偉
461670河南省禹州市人民醫(yī)院普外科
胃十二指腸急性穿孔46例臨床診療分析
王耀偉
461670河南省禹州市人民醫(yī)院普外科
目的:探討胃十二指腸急性穿孔的臨床診療效果。方法:收治胃十二指腸急性穿孔患者46例,隨機(jī)分成胃大部切除術(shù)組16例和穿孔修補(bǔ)術(shù)組30例,胃大部切除術(shù)組行胃大部切除術(shù),穿孔修補(bǔ)術(shù)組行單純穿孔修補(bǔ)術(shù)。對(duì)兩組患者的療效進(jìn)行比較。結(jié)果:穿孔修補(bǔ)術(shù)組手術(shù)時(shí)間、住院時(shí)間明顯短于胃大部切除術(shù)組(P<0.05),穿孔修補(bǔ)術(shù)組并發(fā)癥發(fā)生率明顯低于胃大部切除術(shù)組(P<0.05)。結(jié)論:手術(shù)治療胃十二指腸急性穿孔是首選的治療方法,其中穿孔修補(bǔ)術(shù)具有手術(shù)時(shí)間短,恢復(fù)快,并發(fā)癥少等優(yōu)點(diǎn)。
胃十二指腸急性穿孔;穿孔修補(bǔ)術(shù);胃大部切除術(shù)
胃十二指腸急性穿孔是常見的急腹癥[1],病情進(jìn)展快,需要及時(shí)處理,手術(shù)治療是首選的治療方法。為探討胃十二指腸急性穿孔臨床診療效果,2014年2月-2015年2月收治胃十二指腸急性穿孔患者46例,現(xiàn)報(bào)告如下。
2014年2月-2015年2月收治胃十二指腸急性穿孔患者46例,男40例,女6例,年齡18~76歲,平均44.3歲,隨機(jī)分成胃大部切除術(shù)組16例和穿孔修補(bǔ)術(shù)組30例。其中胃大部切除術(shù)組男14例,女2例,年齡18~73歲,平均44.2歲,其中胃潰瘍穿孔5例,十二指腸潰瘍穿孔11例。穿孔修補(bǔ)術(shù)組男26例,女4例,年齡12~76歲,平均44.5歲,其中胃潰瘍穿孔8例,十二指腸潰瘍穿孔22例。
方法:胃大部切除術(shù)組行胃大部切除術(shù),穿孔修補(bǔ)術(shù)組行單純穿孔修補(bǔ)術(shù),術(shù)后給予抗生素進(jìn)行抗菌治療。術(shù)后進(jìn)行隨訪。
表1 兩組患者臨床療效及潰瘍復(fù)發(fā)比較(x±s)
兩組患者臨床療效及潰瘍復(fù)發(fā)比較:胃大部切除術(shù)組手術(shù)時(shí)間(155.4± 14.2)min,住院時(shí)間(11.2±1.8)d,并發(fā)癥發(fā)生1例,并發(fā)癥發(fā)生率6.25%,潰瘍復(fù)發(fā)1例,復(fù)發(fā)率6.25%;穿孔修補(bǔ)術(shù)組手術(shù)時(shí)間(36.9±5.3)min,住院時(shí)間(6.5± 1.7)d,并發(fā)癥發(fā)生1例,并發(fā)癥發(fā)生率3.3%,潰瘍復(fù)發(fā)2例,復(fù)發(fā)率6.7%,兩組患者在手術(shù)時(shí)間、住院時(shí)間、并發(fā)癥比較,差異有統(tǒng)計(jì)學(xué)意義(P<0.05),潰瘍復(fù)發(fā)方面比較,差異無統(tǒng)計(jì)學(xué)意義(P>0.05),見表1。
胃十二指腸急性穿孔是常見的急腹癥,病情進(jìn)展快,需要及時(shí)處理。據(jù)國外早些年間的研究可以得知,對(duì)潰瘍穿孔進(jìn)行修補(bǔ)的方法是一種既簡單又安全、死亡率低、住院時(shí)間短的最佳治療方法[2,3];但是卻沒有對(duì)潰瘍的病灶進(jìn)行切除以及沒有消除病因,手術(shù)之后有比較高的復(fù)發(fā)率的風(fēng)險(xiǎn)。最近一段時(shí)間以來,由于手術(shù)后加用敏感的抗生素、新型強(qiáng)效的H2受體阻滯劑以及質(zhì)子泵抑制劑,致使穿孔單純修補(bǔ)術(shù)造成的潰瘍的復(fù)發(fā)率顯著降低,潰瘍的治愈率顯著提高。國內(nèi)的一些專家研究也得出[4],單純穿孔的修補(bǔ)術(shù)以及手術(shù)之后內(nèi)科的規(guī)范抑酸、對(duì)幽門螺旋桿菌(H.Pylori)進(jìn)行根除治療明顯地降低了潰瘍的復(fù)發(fā)率,并且手術(shù)后的并發(fā)癥較少,恢復(fù)得也較好[5]。
由本組資料結(jié)果顯示:手術(shù)治療胃十二指腸急性穿孔是首選的治療方法,其中穿孔修補(bǔ)術(shù)具有手術(shù)時(shí)間短,恢復(fù)快,并發(fā)癥少等優(yōu)點(diǎn),值得推廣。采用單純穿孔修復(fù)術(shù)的方法對(duì)患有胃十二指腸潰瘍急性穿孔的患者進(jìn)行治療的臨床效果十分明顯,可以顯著縮短手術(shù)時(shí)間和住院時(shí)間,不會(huì)出現(xiàn)特殊的并發(fā)癥和不良反應(yīng)現(xiàn)象,可以作為臨床對(duì)該類患者進(jìn)行治療的首選方法。
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Analysis of the clinical diagnosis and treatment of acute perforation stomach duodenum in 46 cases
Wang Yaowei
Department of General Surgery,Yuzhou City People's Hospital of Henan Province 461670
Objective:To explore the clinical diagnosis and treatment effect of acute perforation stomach duodenum.Methods:46 patients with acute perforation stomach duodenum were selected.They were randomly divided into the subtotal gastrectomy group with 16 cases and the perforation repair group with 30 cases.The subtotal gastrectomy group was given subtotal gastrectomy.The perforation repair group was given simple perforation repair.The curative effects of two groups were compared.Results:The operation time and hospital stay of the perforation repair group were significantly shorter than those of the subtotal gastrectomy group(P<0.05).The complication incidence rate of the perforation repair group was significantly lower than that of the subtotal gastrectomy group(P<0.05).Conclusion:The operative treatment of acute perforation stomach duodenum is the preferred treatment,and the perforation repair has the advantages of short operation time,quick recovery and less complications.
Acute perforation stomach duodenum;Perforation repair;Subtotal gastrectomy
10.3969/j.issn.1007-614x.2015.33.18