• <tr id="yyy80"></tr>
  • <sup id="yyy80"></sup>
  • <tfoot id="yyy80"><noscript id="yyy80"></noscript></tfoot>
  • 99热精品在线国产_美女午夜性视频免费_国产精品国产高清国产av_av欧美777_自拍偷自拍亚洲精品老妇_亚洲熟女精品中文字幕_www日本黄色视频网_国产精品野战在线观看 ?

    Comparison of imo and Humphrey field analyzer perimeters in glaucomatous eyes

    2021-12-17 02:42:30YoshinoriNakaiKyokoBesshoYukoShonoKaoriTaokaYoshihideNakai
    International Journal of Ophthalmology 2021年12期

    Yoshinori Nakai, Kyoko Bessho, Yuko Shono, Kaori Taoka, Yoshihide Nakai

    Tokai Eye Clinic, 399-Hadokoro-cho, Tsu 514-0009, Japan

    Abstract

    ● KEYWORDS: imo perimeter; visual field diagnosis;diagnostic validation

    INTRODUCTION

    An automated visual field analyzer (perimeter) is indispensable for glaucoma diagnosis and follow-up.However, the conventional equipment is heavy, and a large amount of installation space is needed, and the examining room must be dark. For an examination, patients must sit in front of the visual field analyzer; therefore, bedside examinations are not possible. Recently, however, a head-mounted device, the imo perimeter (Crewt Medical Systems, Inc., Tokyo, Japan),has been developed to be lightweight (1.8 kg) and to be used in a brightly lit room. It can help clinicians perform visual field inspections and observe the central and peripheral visual fields of up to 30 degrees in both eyes simultaneously within a short time period (Figure 1)[1-11].

    We compared glaucoma detection sensitivities, diagnostic abilities in addition to the correlation of each parameter and examination time of the Humphrey field analyzer (HFA;Humphrey Instruments, Dublin, CA, USA), which is currently in wide use, with those of imo perimeters.

    With the imo perimeter, the left and right pupils are monitored individually with a near-infrared camera for fixation disparity,which reduces the examination time (Figure 2). In addition,with the imo perimeter, a transmissive liquid crystal display at full high-definition resolution and a high-brightness lightemitting diode backlight are used in the same conditions as those of the HFA perimeter. Furthermore, targets are shown to the left and right eyes of subjects separately but simultaneously by independent left and right optical systems. In the visual field test, the fixed target is visually fused, and patients fixate on the target with both eyes open (Figure 3).

    The imo perimeter has a mode of 24 plus (78 test points) to which a 10-2 visual field is added (so that it is partially like the HFA perimeter with its visual fields of 30-2, 24-2, and 10-2),as well as a mode of 24 plus 1 (36 points), in which the points are preferentially focused on sites in which disease is likely to occur. To examine the correlation of the measurements made with the HFA and imo perimeters for mild to severe glaucoma, we used a 30-2 examination program (widely used in glaucoma diagnosis), in which a 30-degree visual field was measured with intervals of 6 degrees.

    SUBJECTS AND METHODS

    Figure 1 Head-mounted imo perimeter weighing 1.8 kg It can be used in a well-lit room, and it enables both eyes to be examined quickly and simultaneously.

    Figure 2 Simultaneous monitoring of binocular fixation by imo perimeter, with automatic tracking correction (from side to side and up and down), and pupil diameter measurement.

    Figure 3 The test target was presented randomly to either eye under a nonocclusion condition, and the patient was not aware of which eye was being tested.

    Ethical Approval This study was conducted in compliance with the tenets of the Helsinki Declaration, and all participants provided written informed consent.Visual field tests were performed with both the HFA and imo perimeters on the same day for each patient on 128 eyes of 64 patients with glaucoma and 40 normal eyes of 20 healthy people, all of whom were examined at the Tokai Eye Clinic,Tsu, Japan, between October 2018 and February 2019. Patients with glaucoma who completely understood the contents of the visual field tests and demonstrated good visual fixation in testing were selected.

    Table 1 Characteristics of the participants in the study

    Using Pearson’s correlation coefficient, we compared the parameters—the mean deviation and defect (MD), the pattern standard deviation (PSD), and the visual field index (VFI)—as measured by both the HFA and imo perimeters. We calculated the detection sensitivity by using Bland-Altman analysis, the diagnostic ability by the area under the receiver operating characteristic curve (AUC), and, with thettest, the examination time.

    Background of Patients with Glaucoma The participants with glaucoma had a spherical equivalent of -6 to +3 D,astigmatism of ±2.5 D, and best-corrected visual acuity(logMAR) of 0.2 to 0.08. They had not undergone eye surgery in the past and had no eye disease except glaucoma. The patients were 18 to 72 years of age, with an average age of 59.5±13.5y; 25 were men, and 39 were women (Table 1).

    RESULTS

    In the 40 normal eyes, the mean examination times were 12±1.4min with the HFA perimeter and 8.3±1.8min with the imo perimeter (P<0.001). In the 128 glaucomatous eyes, the mean examination times were 16.2±2.5min with the HFA perimeter and 12.0±2.5min with the imo perimeter (P<0.001).Thus the examinations of both the normal eyes and the eyes with glaucoma were performed in a significantly short time(P<0.001; Table 2).

    Pearson’s correlation coefficients with the HFA and imo perimeters in the 128 eyes with glaucoma were 0.886(P<0.001) for MD,0.814(P<0.001) for PSD, and 0.871 (P<0.001) for VFI; strong correlations were thus noted (Figure 4). In the 40 normal eyes,the correlation coefficients were 0.248(P<0.124) for MD,0.111(P<0.496) for PSD, and 0.028(P<0.864) for VFI.

    Figure 4 In 128 glaucomatous eyes, the imo perimeter and the HFA perimeter’s measurements of MD (r=0.886, P<0.001), PSD (r=0.814,P<0.001), and VFI (r=0.871, P<0.001) were strongly and positively correlated.

    Figure 5 Displays of the visual field by the HFA and imo perimeters In case 1 (mild glaucoma), there was no difference in the displays; in case 2, 3 and 4 (advanced glaucoma), however, the differences were obvious.

    Table 2 Examination time of imo and HFA perimeters min, mean±SD

    To compare the MD, PSD, and VFI measured by both the perimeters, we performed the Bland-Altman analysis because even if those parameters of the HFA and imo perimeters were correlated, we suspected a difference would reflect a worse rate of glaucoma. Figure 5 illustrates the results of a comparison of the visual field findings of the HFA and imo perimeters in patients 1, 2, 3, and 4. Patient 1, in whom glaucoma was mild,showed no difference in parameters, whereas patients 2, 3 and 4, in whom the glaucoma was advanced, did show differences.The results of the Bland-Altman analysis are shown in Figure 6, in which the vertical axis reflects the difference between the imo and HFA perimeters and the horizontal axis shows the average values of the HFA and imo perimeters. The distribution was fan-shaped, whereby the worse the glaucoma was (horizontal axis), the greater was the difference in results between the imo and HFA perimeters. This finding reflects a proportional error.

    The diagnostic ability of both perimeters was examined with AUC (Figure 7). For MD, the AUCs were 0.911 for the imo perimeter and 0.819 for the HFA perimeter; for PSD, they were 0.885 for the imo perimeter and 0.890 for the HFA perimeter;and for VFI, they were 0.882 for the imo perimeter and 0.872 for the HFA perimeter. Both the imo and HFA perimeters demonstrated high diagnostic ability, and no significant difference in diagnostic ability was noted between them.

    DISCUSSION

    In addition to 30-2, 24-2, and 10-2 perimetry inspection modes, which the HFA perimeter has, the imo perimeter has a mode termed “24 plus” (78 test points). This mode consists of some of the test points of 10-2 added to those of 24-2 (36 test points), in which test points are preferentially arranged at sites of the 24 plus mode in which disease is likely to occur. An algorithm termed “AIZE-Rapid” (Crewt Medical Systems) can be used to further shorten inspection time. The imo perimeter is highly reliable because it has two independent optical systems that can both perform a visual field examination with both the patient’s eyes open and perform eye tracking of the pupil.

    Figure 6 Bland-Altman analysis was used to compare MD, PSD, and VFI measurements by the HFA perimeter and the imo perimeter For glaucoma eye a proportional error was observed. The results show the fan-shaped distribution, where the worse is the glaucoma (horizontal axis), the greater is the difference between imo and HFA results.

    Figure 7 The diagnostic abilities of both the HFA and the imo perimeters were significant; AUC was 0.8 or greater in the MD, PSD, and VFI measurements, and the maximum value of the AUC was 0.911 for the MD measurement by the imo perimeter.

    In this study, 128 eyes of 64 glaucoma patients and 40 eyes of 20 healthy people were examined with the 30-2 mode,which is widely currently used in glaucoma testing. The current basic measurement of static visual field consists of examining approximately 70 measurements points within the central 30 degrees with intervals of 6 degrees, as indicated by the HFA perimeter 30-2 mode. The arrangement of the gridlike measurement points with intervals of 6 degrees has poor sensitivity for early glaucoma detection and macular disease;therefore, the use of an additional macular mode such as 10-2 is recommended.

    The purpose of this study was to investigate the correlation between imo and HFA perimeter and the reliability of imo perimeter. Therefore, in many cases, abnormalities appeared early within 30 degrees of the visual field center. In 30-2,comparison of measurement time of two perimeters, the correlation of each parameter, Bland-Altman analysis, and diagnostic ability with AUC were examined.

    In the comparison between the widely used HFA and the Octopus perimeters[12]and in comparison with the KOWA AP-7000 perimeter[13]reported strong correlations. With regard to the effect of different arrangements, these investigators reported that there was no substantial difference between the 30-2 and 24-2 modes to the HFA perimeter[14-15]. As our objective was to examine the correlation between the imo and HFA perimeters and the reliability of the imo perimeter, we compared the measurement times of both perimeters by using the 30-2 mode. This is the mode in which abnormalities caused by many diseases are expressed earliest within the central 30 degrees of the visual field. We checked the correlation of each parameter, performed a Bland-Altman analysis, and used the AUC to examine the glaucoma diagnostic ability of both perimeters.

    Khouryet al[14]compared the examination times of the HFA with 24-2 and 30-2 modes, demonstrating an average of 10min and 24s with the 24-2 mode and an average of 14min and 24s with the 30-2 mode. Our examinations of 128 glaucomatous eyes and 40 normal eyes were significantly shorter with the imo perimeter than with the HFA perimeter:shorter by 4.2min for glaucomatous eyes and by 3.8min for normal eyes (Table 2). Because the imo perimeter is capable of measuring both eyes simultaneously in a brightly lit room,the burden on patients was reduced. It is thought that the examination time with the imo perimeter is shorter because it individually monitors the fixation of the left and right pupils and automatically corrects fixation disparity and because the AIZE-Rapid algorithm further speeds up examination.

    Pearson’s correlation coefficients of MD, PSD, and VFI were 0.886, 0.814, and 0.871 (allP<0.001), respectively, and the correlations were significantly positive (Figure 4). In normal eyes, the reason that the MD, PSD, and VFI were 0.248, 0.111,and 0.028 and were lower than those in glaucomatous eyes was probably because the parameter values of normal eyes was dense. Even though there was a positive correlation between the two perimeters, we performed a Bland-Altman analysis to examine whether there was any difference as a result of the progression of glaucoma. The analysis showed that the difference between the imo and HFA perimeters tended to increase as glaucoma progressed, and a proportional error was observed in MD, PSD, and VFI in all cases (Figure 5). Thus caution is required in the determinations of these parameters because the difference between results obtained with the imo and HFA perimeters increases as the visual field disturbance progresses. This demonstrates that the measurements obtained from the imo may indicate a higher rate of worsening of glaucoma than previously realized and that this rate may increase. However, there may be some cases in which the measurements improve.

    The diagnostic ability of both perimeters was examined in receiver operating characteristic analysis (Figure 6). The highest AUC (0.911) was observed in MD with the imo perimeter(95% CI: 0.867 to 0.955). All MD, PSD, and VFI values exceeded 0.8 for both the imo and HFA perimeters, and the diagnostic abilities of the two perimeters were all significant (P<0.001).Moreover, the AUC of the MD was significantly higher for the imo perimeter than for the HFA perimeter.

    In addition to the head-mounted configuration, other advantages of the imo perimeter are its light weight and small size, which facilitate easy handling. These features not only allow patients to be examined in bed but also expand the range of clinical applications, including the conducting of examinations in a small space[16-19].

    The National Aeronautics and Space Administration is studying and elucidating symptoms of space flight-associated neuroocular syndrome (SANS), which occur in the whole body,nerves, and eyes during long space flights. Symptoms such as optic disc edema, globe flattening, choroidal and retinal folds,hyperopic refractive error shifts, and infarcts in nerve fiber layers have been reported to occur during long-term residence in a space station[20-21]. The imo perimeter will be a useful apparatus for performing visual field examinations in a space station.

    ACKNOWLEDGEMENTS

    Conflicts of Interest:Nakai Y, None; Bessho K, None;Shono Y, None; Taoka K, None; Nakai Y, None.

    亚洲午夜精品一区,二区,三区| 国产高清视频在线播放一区| 夜夜看夜夜爽夜夜摸| 国产精品免费视频内射| 一级a爱视频在线免费观看| 久久久久久久久中文| www.熟女人妻精品国产| 精品午夜福利视频在线观看一区| 可以免费在线观看a视频的电影网站| 夜夜躁狠狠躁天天躁| 侵犯人妻中文字幕一二三四区| 久久国产精品男人的天堂亚洲| 久久久精品欧美日韩精品| 亚洲一卡2卡3卡4卡5卡精品中文| 国产成人精品久久二区二区免费| 国产精品综合久久久久久久免费 | 又大又爽又粗| 亚洲第一电影网av| 黄网站色视频无遮挡免费观看| 午夜a级毛片| 男女之事视频高清在线观看| 午夜福利成人在线免费观看| 窝窝影院91人妻| 一级毛片高清免费大全| 91精品国产国语对白视频| 啦啦啦韩国在线观看视频| 国产熟女xx| 一本综合久久免费| 咕卡用的链子| 久久久久国产精品人妻aⅴ院| 777久久人妻少妇嫩草av网站| 亚洲中文字幕日韩| 欧美日韩黄片免| 日本免费一区二区三区高清不卡 | 叶爱在线成人免费视频播放| 亚洲性夜色夜夜综合| 国产精品 国内视频| 午夜免费激情av| 亚洲人成电影观看| bbb黄色大片| 国产精品秋霞免费鲁丝片| 首页视频小说图片口味搜索| 天堂影院成人在线观看| 高潮久久久久久久久久久不卡| 亚洲av成人一区二区三| 日韩精品中文字幕看吧| 麻豆久久精品国产亚洲av| 午夜影院日韩av| 午夜免费观看网址| 精品国产乱码久久久久久男人| 精品久久久久久久毛片微露脸| 啦啦啦 在线观看视频| 亚洲久久久国产精品| 午夜福利免费观看在线| 性少妇av在线| 好看av亚洲va欧美ⅴa在| 人人妻人人澡欧美一区二区 | 欧美国产精品va在线观看不卡| 亚洲成人精品中文字幕电影| 亚洲五月天丁香| 免费久久久久久久精品成人欧美视频| 黄网站色视频无遮挡免费观看| 亚洲第一青青草原| 午夜精品在线福利| 国产成人精品久久二区二区免费| 亚洲国产毛片av蜜桃av| 亚洲国产欧美一区二区综合| 色尼玛亚洲综合影院| 九色亚洲精品在线播放| 欧美黄色片欧美黄色片| 国产色视频综合| 在线播放国产精品三级| 亚洲三区欧美一区| 久久久久久国产a免费观看| 在线观看日韩欧美| 男男h啪啪无遮挡| 欧美+亚洲+日韩+国产| 啦啦啦 在线观看视频| bbb黄色大片| 午夜激情av网站| 久久婷婷人人爽人人干人人爱 | 少妇粗大呻吟视频| 欧美日韩亚洲综合一区二区三区_| 欧美色欧美亚洲另类二区 | 麻豆av在线久日| av天堂久久9| 亚洲三区欧美一区| 一个人免费在线观看的高清视频| 欧美成人免费av一区二区三区| 色婷婷久久久亚洲欧美| 亚洲,欧美精品.| 亚洲色图 男人天堂 中文字幕| 人妻丰满熟妇av一区二区三区| 老司机深夜福利视频在线观看| 亚洲色图av天堂| 黑人巨大精品欧美一区二区蜜桃| 国产精品久久久久久精品电影 | 久久香蕉国产精品| 精品免费久久久久久久清纯| 黄片大片在线免费观看| 99精品久久久久人妻精品| 亚洲国产精品久久男人天堂| 精品一区二区三区视频在线观看免费| 亚洲精品美女久久久久99蜜臀| 好男人在线观看高清免费视频 | 亚洲全国av大片| 露出奶头的视频| 两人在一起打扑克的视频| 免费在线观看视频国产中文字幕亚洲| 一进一出好大好爽视频| 国产麻豆成人av免费视频| 色综合婷婷激情| 亚洲美女黄片视频| 国产高清有码在线观看视频 | 18禁观看日本| 日本 av在线| 国产一卡二卡三卡精品| 国产精品自产拍在线观看55亚洲| 99在线视频只有这里精品首页| 波多野结衣巨乳人妻| 国产野战对白在线观看| av超薄肉色丝袜交足视频| 中文字幕最新亚洲高清| 不卡一级毛片| 免费女性裸体啪啪无遮挡网站| 国产成人啪精品午夜网站| 欧美成人午夜精品| 极品教师在线免费播放| 天堂影院成人在线观看| 女人高潮潮喷娇喘18禁视频| 亚洲av第一区精品v没综合| 在线播放国产精品三级| 国产精品影院久久| a级毛片在线看网站| 亚洲在线自拍视频| 亚洲自拍偷在线| 啪啪无遮挡十八禁网站| 91精品国产国语对白视频| 午夜福利18| a级毛片在线看网站| 高潮久久久久久久久久久不卡| 国产精品影院久久| 黄色视频,在线免费观看| 波多野结衣一区麻豆| 精品久久久久久成人av| 人人澡人人妻人| 美女国产高潮福利片在线看| 亚洲专区中文字幕在线| 中文字幕人妻丝袜一区二区| 欧美丝袜亚洲另类 | 国产欧美日韩一区二区精品| 色婷婷久久久亚洲欧美| 19禁男女啪啪无遮挡网站| 日本撒尿小便嘘嘘汇集6| 亚洲最大成人中文| 国产一卡二卡三卡精品| 成人国语在线视频| 国产一级毛片七仙女欲春2 | 精品久久蜜臀av无| 身体一侧抽搐| 人成视频在线观看免费观看| 久久 成人 亚洲| 99国产极品粉嫩在线观看| 免费高清视频大片| 亚洲精品中文字幕一二三四区| 欧美人与性动交α欧美精品济南到| 中出人妻视频一区二区| 亚洲精品av麻豆狂野| 日韩精品中文字幕看吧| 午夜福利18| 香蕉丝袜av| 免费在线观看完整版高清| 一区二区日韩欧美中文字幕| 国产精品自产拍在线观看55亚洲| av片东京热男人的天堂| av电影中文网址| 国产av在哪里看| 嫩草影院精品99| 日本撒尿小便嘘嘘汇集6| 久久精品国产综合久久久| 少妇粗大呻吟视频| 午夜福利,免费看| 亚洲一码二码三码区别大吗| 亚洲欧美激情综合另类| 国产精品一区二区在线不卡| 亚洲一区中文字幕在线| 精品久久久久久,| 亚洲精品久久国产高清桃花| 国产成+人综合+亚洲专区| 久热这里只有精品99| 欧美人与性动交α欧美精品济南到| 免费在线观看视频国产中文字幕亚洲| 国产一区二区激情短视频| 狂野欧美激情性xxxx| 成人特级黄色片久久久久久久| 俄罗斯特黄特色一大片| 中文字幕久久专区| 婷婷六月久久综合丁香| 黄色片一级片一级黄色片| 国产1区2区3区精品| 日本黄色视频三级网站网址| 岛国视频午夜一区免费看| 桃色一区二区三区在线观看| 国产午夜福利久久久久久| 精品久久久久久久毛片微露脸| 色尼玛亚洲综合影院| 日韩一卡2卡3卡4卡2021年| 女性被躁到高潮视频| 男女床上黄色一级片免费看| 美女扒开内裤让男人捅视频| 午夜免费成人在线视频| 久9热在线精品视频| 亚洲最大成人中文| 欧美激情极品国产一区二区三区| 亚洲欧洲精品一区二区精品久久久| 大型黄色视频在线免费观看| 午夜免费激情av| 国产成+人综合+亚洲专区| 国产成年人精品一区二区| 国产97色在线日韩免费| 久久久久久人人人人人| 又大又爽又粗| 亚洲av五月六月丁香网| 亚洲av电影在线进入| www.熟女人妻精品国产| 国产又爽黄色视频| 精品国产一区二区久久| 免费在线观看影片大全网站| 国产精品久久视频播放| 久久精品亚洲熟妇少妇任你| 免费高清在线观看日韩| 人妻丰满熟妇av一区二区三区| 中文字幕人成人乱码亚洲影| 日本撒尿小便嘘嘘汇集6| 精品国产亚洲在线| 中亚洲国语对白在线视频| 亚洲中文日韩欧美视频| 午夜免费观看网址| 国产精品亚洲av一区麻豆| 麻豆久久精品国产亚洲av| 欧美在线一区亚洲| 美国免费a级毛片| 国产精品二区激情视频| 成人18禁在线播放| 成人三级黄色视频| 国产麻豆69| 九色亚洲精品在线播放| 国产高清有码在线观看视频 | 国产成人精品无人区| 国产成年人精品一区二区| 男女下面进入的视频免费午夜 | 一本久久中文字幕| 老熟妇乱子伦视频在线观看| 免费女性裸体啪啪无遮挡网站| 啦啦啦观看免费观看视频高清 | 窝窝影院91人妻| 国产主播在线观看一区二区| 三级毛片av免费| 在线观看免费视频日本深夜| 色播亚洲综合网| netflix在线观看网站| 亚洲,欧美精品.| 亚洲avbb在线观看| 亚洲精品一区av在线观看| 亚洲色图 男人天堂 中文字幕| 欧美日韩精品网址| 高清黄色对白视频在线免费看| 色综合婷婷激情| 亚洲成av片中文字幕在线观看| 精品午夜福利视频在线观看一区| 日韩成人在线观看一区二区三区| 国产国语露脸激情在线看| 激情视频va一区二区三区| 满18在线观看网站| 又黄又粗又硬又大视频| 欧美日韩亚洲综合一区二区三区_| 欧美最黄视频在线播放免费| 亚洲成av片中文字幕在线观看| 法律面前人人平等表现在哪些方面| 免费看a级黄色片| 国产av又大| 777久久人妻少妇嫩草av网站| 日韩欧美免费精品| 91在线观看av| 久久精品人人爽人人爽视色| 日日爽夜夜爽网站| 一二三四社区在线视频社区8| www.熟女人妻精品国产| 精品人妻在线不人妻| av片东京热男人的天堂| 人人妻,人人澡人人爽秒播| 99在线视频只有这里精品首页| 精品不卡国产一区二区三区| 久久精品91无色码中文字幕| 国语自产精品视频在线第100页| 精品国产乱码久久久久久男人| 久久国产亚洲av麻豆专区| 国产成年人精品一区二区| 多毛熟女@视频| 日韩成人在线观看一区二区三区| 十分钟在线观看高清视频www| 一区二区三区高清视频在线| av福利片在线| 精品电影一区二区在线| 在线观看日韩欧美| ponron亚洲| 香蕉国产在线看| 国产精品亚洲一级av第二区| 99riav亚洲国产免费| 欧美日韩精品网址| 久久久久久久久久久久大奶| 97人妻天天添夜夜摸| 亚洲七黄色美女视频| 韩国av一区二区三区四区| 女性生殖器流出的白浆| 麻豆一二三区av精品| 亚洲av成人av| 精品国产乱子伦一区二区三区| 他把我摸到了高潮在线观看| 级片在线观看| 在线免费观看的www视频| 法律面前人人平等表现在哪些方面| 美女免费视频网站| av片东京热男人的天堂| 久久人人精品亚洲av| 一进一出抽搐动态| 神马国产精品三级电影在线观看 | 99riav亚洲国产免费| 97人妻天天添夜夜摸| 亚洲av熟女| 亚洲va日本ⅴa欧美va伊人久久| 成在线人永久免费视频| netflix在线观看网站| 久久久国产精品麻豆| 成人欧美大片| 美女高潮到喷水免费观看| 91老司机精品| 天堂动漫精品| 中文字幕av电影在线播放| 亚洲av美国av| 高潮久久久久久久久久久不卡| 日韩欧美三级三区| 精品国产乱子伦一区二区三区| 88av欧美| 人妻丰满熟妇av一区二区三区| 欧美黄色片欧美黄色片| 日韩大尺度精品在线看网址 | 香蕉久久夜色| 一夜夜www| 欧美 亚洲 国产 日韩一| 少妇裸体淫交视频免费看高清 | 中出人妻视频一区二区| 一a级毛片在线观看| 亚洲一区高清亚洲精品| 国产xxxxx性猛交| 久久久国产成人精品二区| 村上凉子中文字幕在线| 欧美成人免费av一区二区三区| 国产成人系列免费观看| 精品午夜福利视频在线观看一区| 亚洲片人在线观看| 欧美大码av| 黄片小视频在线播放| 叶爱在线成人免费视频播放| 黑人操中国人逼视频| 嫩草影院精品99| netflix在线观看网站| 日韩视频一区二区在线观看| 精品久久久精品久久久| 两个人视频免费观看高清| 国产精品乱码一区二三区的特点 | 动漫黄色视频在线观看| 午夜精品久久久久久毛片777| 国产一区二区三区视频了| 亚洲色图 男人天堂 中文字幕| 色哟哟哟哟哟哟| www.www免费av| 久久精品亚洲精品国产色婷小说| 亚洲精品国产精品久久久不卡| 久久久久精品国产欧美久久久| 黄色女人牲交| 国产精品一区二区免费欧美| 国产一区二区在线av高清观看| 精品久久久久久久人妻蜜臀av | 黄片播放在线免费| 天堂√8在线中文| 国产99久久九九免费精品| 国产一区二区三区综合在线观看| 丝袜美足系列| 久久人妻福利社区极品人妻图片| 国产免费男女视频| 99国产精品一区二区蜜桃av| 免费在线观看视频国产中文字幕亚洲| 一个人观看的视频www高清免费观看 | 日本黄色视频三级网站网址| av福利片在线| 亚洲精品一区av在线观看| 成人国语在线视频| 国产主播在线观看一区二区| 九色国产91popny在线| 99国产精品免费福利视频| 国产精品电影一区二区三区| or卡值多少钱| 757午夜福利合集在线观看| 亚洲国产精品成人综合色| 一级a爱视频在线免费观看| 午夜福利在线观看吧| 日韩中文字幕欧美一区二区| 在线观看免费午夜福利视频| 免费看a级黄色片| 亚洲第一欧美日韩一区二区三区| 久久亚洲精品不卡| 国产日韩一区二区三区精品不卡| 欧美激情极品国产一区二区三区| 女人爽到高潮嗷嗷叫在线视频| 性色av乱码一区二区三区2| 日韩精品中文字幕看吧| 午夜免费激情av| 老司机靠b影院| 国产成人一区二区三区免费视频网站| 美女大奶头视频| 欧洲精品卡2卡3卡4卡5卡区| 亚洲av美国av| 色综合婷婷激情| 国产亚洲精品久久久久5区| 亚洲午夜精品一区,二区,三区| 免费看十八禁软件| 午夜视频精品福利| 久久久国产成人精品二区| 男女下面进入的视频免费午夜 | 黑人操中国人逼视频| 精品免费久久久久久久清纯| 精品少妇一区二区三区视频日本电影| 久久久国产成人免费| www.自偷自拍.com| 久久久久九九精品影院| 成人av一区二区三区在线看| 老司机午夜十八禁免费视频| 男人舔女人下体高潮全视频| 精品第一国产精品| 亚洲中文av在线| 亚洲av片天天在线观看| 69av精品久久久久久| 国产亚洲精品久久久久久毛片| 久久午夜亚洲精品久久| 亚洲少妇的诱惑av| 亚洲国产精品久久男人天堂| 长腿黑丝高跟| 久久精品亚洲精品国产色婷小说| 午夜福利在线观看吧| 亚洲精品国产区一区二| 日韩一卡2卡3卡4卡2021年| 巨乳人妻的诱惑在线观看| √禁漫天堂资源中文www| 国产精品,欧美在线| 免费观看精品视频网站| 久久中文字幕人妻熟女| 国产精品一区二区精品视频观看| 一区在线观看完整版| 婷婷精品国产亚洲av在线| 成人亚洲精品av一区二区| 亚洲第一青青草原| 亚洲午夜理论影院| 电影成人av| 午夜两性在线视频| av超薄肉色丝袜交足视频| 女性被躁到高潮视频| 免费女性裸体啪啪无遮挡网站| 精品久久久精品久久久| 免费搜索国产男女视频| 亚洲国产欧美日韩在线播放| 女人精品久久久久毛片| 免费av毛片视频| 久久青草综合色| 俄罗斯特黄特色一大片| 亚洲欧美日韩另类电影网站| 99精品久久久久人妻精品| 精品久久久久久,| 黄色丝袜av网址大全| 在线天堂中文资源库| 欧美乱码精品一区二区三区| 18美女黄网站色大片免费观看| 色哟哟哟哟哟哟| 最新在线观看一区二区三区| 亚洲激情在线av| 中文字幕av电影在线播放| 精品免费久久久久久久清纯| 精品国产超薄肉色丝袜足j| 免费在线观看亚洲国产| 国产蜜桃级精品一区二区三区| 免费观看精品视频网站| а√天堂www在线а√下载| 成人特级黄色片久久久久久久| 非洲黑人性xxxx精品又粗又长| 日韩 欧美 亚洲 中文字幕| 精品一区二区三区av网在线观看| 99国产综合亚洲精品| 久久国产精品影院| x7x7x7水蜜桃| 少妇被粗大的猛进出69影院| 日日摸夜夜添夜夜添小说| 制服丝袜大香蕉在线| 女同久久另类99精品国产91| 亚洲人成伊人成综合网2020| 黄色女人牲交| 亚洲av片天天在线观看| 18美女黄网站色大片免费观看| 天天躁夜夜躁狠狠躁躁| 法律面前人人平等表现在哪些方面| 久久精品影院6| 99国产精品一区二区三区| 午夜福利视频1000在线观看 | √禁漫天堂资源中文www| 日韩三级视频一区二区三区| 岛国在线观看网站| 好男人在线观看高清免费视频 | 亚洲aⅴ乱码一区二区在线播放 | 夜夜看夜夜爽夜夜摸| 日本vs欧美在线观看视频| 久久婷婷人人爽人人干人人爱 | 69av精品久久久久久| 免费在线观看影片大全网站| 精品日产1卡2卡| АⅤ资源中文在线天堂| 欧美日韩瑟瑟在线播放| 一级作爱视频免费观看| 男女下面进入的视频免费午夜 | 日韩中文字幕欧美一区二区| 国产97色在线日韩免费| 在线免费观看的www视频| 女人爽到高潮嗷嗷叫在线视频| 又大又爽又粗| 91成人精品电影| 亚洲精品国产色婷婷电影| 久久久久久大精品| 精品少妇一区二区三区视频日本电影| 日韩一卡2卡3卡4卡2021年| 精品国产美女av久久久久小说| 波多野结衣巨乳人妻| 最近最新免费中文字幕在线| 91字幕亚洲| 亚洲国产中文字幕在线视频| 久久香蕉国产精品| 国产精品一区二区精品视频观看| 美女 人体艺术 gogo| 久久精品aⅴ一区二区三区四区| 国产精品电影一区二区三区| 夜夜爽天天搞| 黑人巨大精品欧美一区二区蜜桃| 国产人伦9x9x在线观看| 国产精品av久久久久免费| 一边摸一边做爽爽视频免费| 十分钟在线观看高清视频www| 深夜精品福利| 99国产精品一区二区三区| 99在线视频只有这里精品首页| 男人舔女人下体高潮全视频| 男男h啪啪无遮挡| 视频在线观看一区二区三区| 男女午夜视频在线观看| 精品久久久久久久久久免费视频| 黄频高清免费视频| 午夜视频精品福利| 日本在线视频免费播放| 国产av精品麻豆| 久久精品91蜜桃| 国产片内射在线| 国产精品爽爽va在线观看网站 | av中文乱码字幕在线| 欧美久久黑人一区二区| 免费女性裸体啪啪无遮挡网站| 身体一侧抽搐| 亚洲精品国产一区二区精华液| 成人亚洲精品一区在线观看| 亚洲中文字幕日韩| 99久久综合精品五月天人人| 美女高潮到喷水免费观看| 麻豆成人av在线观看| 久久久国产成人精品二区| 亚洲精品美女久久av网站| 曰老女人黄片| 日本vs欧美在线观看视频| 深夜精品福利| 亚洲午夜精品一区,二区,三区| 热99re8久久精品国产| 一进一出好大好爽视频| 欧美绝顶高潮抽搐喷水| 精品熟女少妇八av免费久了| 国产欧美日韩一区二区三| 好看av亚洲va欧美ⅴa在| 欧美色视频一区免费| 两个人免费观看高清视频| 国产亚洲精品av在线| 后天国语完整版免费观看| 在线观看一区二区三区| 黑人操中国人逼视频| 真人一进一出gif抽搐免费| 日韩欧美一区视频在线观看| av电影中文网址| 欧美日韩一级在线毛片| 久久天堂一区二区三区四区| 天天一区二区日本电影三级 | 国产主播在线观看一区二区| 亚洲国产日韩欧美精品在线观看 | 亚洲中文日韩欧美视频| 在线观看免费日韩欧美大片| av在线播放免费不卡| 咕卡用的链子| 久久香蕉激情| 91麻豆精品激情在线观看国产| 欧美 亚洲 国产 日韩一| 人人妻人人澡人人看| 深夜精品福利| 亚洲精品一卡2卡三卡4卡5卡| 国产精品亚洲av一区麻豆|