《實驗動物與比較醫(yī)學》2021年第41卷總目次

·創(chuàng)刊40周年專家論壇·

從人類基因組計劃到精準醫(yī)學——比較醫(yī)學的發(fā)展趨勢與挑戰(zhàn)·········································· 趙國屏(1)

基于能力提升的我國實驗動物資源發(fā)展愿景···································································· 賀爭鳴(85)

腦缺血動物模型的制備及評估進展························································ 胡志斌，黃 纓，丁玉強(271)

復雜疾病小鼠模型構建新策略：類精子單倍體胚胎干細胞介導的半克隆技術··········································································································································· 賴梭梅，丁一夫，李勁松(369)

CNAS實驗動物機構認可進展························································································ 吳孝槐(384)

利用中國倉鼠制備疾病模型的優(yōu)勢與進展······················ 高繼萍，陳朝陽，軒瑞晶，張銳虎，宋國華(392)

·創(chuàng)刊40周年專題：各地實驗動物科學發(fā)展·

西雙版納會議與湖北省實驗動物科技發(fā)展40年歷程·························································· 唐利軍(9)

陜西省實驗動物工作近10年發(fā)展歷程····················································· 師長宏，劉恩岐，張 海(14)

黑龍江省實驗動物管理現(xiàn)狀與發(fā)展對策············································································································· 李寶龍，王玉娥，司昌德，李昌文，劉懷然，郭守利，韓凌霞，劉景利，李永明，陳洪巖(181)

山西省實驗動物資源共享服務平臺建設現(xiàn)狀及發(fā)展對策············· 張銳虎，王春芳，宋國華，陳朝陽(190)

江蘇省實驗動物行政許可現(xiàn)狀······································· 陳 林，艾 曼，徐 航，漆重陽，施愛民(284)

云南省實驗動物工作40年發(fā)展歷程與思考················································ 罕園園，李娜，代解杰(399)

·創(chuàng)刊40周年專題：期刊發(fā)展·

《實驗動物與比較醫(yī)學》創(chuàng)刊40年重要文獻回顧······························································· 高 誠(17)

《實驗動物與比較醫(yī)學》創(chuàng)刊40年重點文獻回顧（續(xù)）······················································· 高 誠(169)

·實驗動物福利與倫理·

2020版美國獸醫(yī)協(xié)會動物安樂死指南解析········································································································· 盧 今，張 穎，潘學營，王 劍，嚴國鋒，周 晶，朱 蓮，陳學進，李 垚，龐萬勇(195)

小鼠生活籠實驗引入適應期的必要性研究······················ 尹 媛，陸 璐，王 蘊，楊 景，付鶴玲(358)

·人類疾病動物模型·

慢性低氧性肺動脈高壓大鼠動脈血氣分析指標的變化及其意義····· 張舒婷，姚青青，李宜珊，施熠煒(27)

聚糖硫酸鈉不同給藥方式建立小鼠潰瘍性結腸炎模型········ 趙亞妮，李 瑤，張 妍，王四旺，安軍明(33)

雌性侏儒癥大鼠繁殖性能初探···················································· 焦淑凡，徐龍妹，華征宇，姚菊芳(40)

高脂飼料誘導代謝性疾病動物模型·········· 羅建波，李軍暉，王海江，周小玉，曾 濤，周 佳，朱獻軍(70)

免疫功能正常的HBV cccDNA小鼠模型用于苦參堿和青蒿素抑制HBV的藥效評價··············································· 伍 悅，呂小琴，劉 陽，向 霞，趙中華，徐如青，潘朔寒，何明忠，張華堂，賴國旗(108)

皮膚光老化小鼠模型的構建及效果評估····························································· 孔 悅，郭 硯(116)

肝螺桿菌感染促進高脂飼料誘導的小鼠非酒精性脂肪性肝病進展·································································································································· 沈 宸，吳志浩，殷 俊，朱立麒，張 泉(122)

1型糖尿病早期大鼠空腸的神經功能及組織形態(tài)學變化····································································································································· 王 嫚，祗明花，耿旭芳，佟苗苗，梁紅玉，趙 丁(131)

五苓散對高脂血癥模型貴州小型豬的治療作用·························································································································· 張 慧，吳延軍，姚 瑾，陸濤峰，王郭琦，趙 海，姚 剛，吳曙光(138)

一種大鼠跑臺抗阻訓練模型的構建························································ 藺海旗，王 震，林文弢(143)

松果體損傷大鼠模型3種制備方法的比較研究···························· 王丹妮，宋美卿，楊 鈐，馮瑪莉(215)

人腦膠質瘤大鼠移植模型的初步建立···························· 譚鄧旭，吳朋朋，趙 勇，師長宏，葛 煦(220)

肝螺桿菌感染對葡聚糖硫酸鈉誘導小鼠慢性結腸炎模型的影響······································································································································ 吳志浩，沈 宸，殷 俊，朱立麒，張 泉(226)

慢性間歇性低氧模型大鼠的甲狀腺功能分析·········································· 田 慧，高 隆，王澤輝(232)

高原多臟器功能障礙綜合征蕨麻豬模型C反應蛋白及炎性因子的變化···································································································· 肖 攀，牛廷獻，羅曉紅，王紅義，郭曉宇，陸 璐，馮小明(238)

小鼠脊髓損傷打擊模型精細行為的比較研究······ 顏義彤，白 帆，荊瀛黎，王立淼，李子晗，于 艷(290)

肉芽腫小葉性乳腺炎大鼠模型建立初探····································································································································· 左禧萌，史曉光，劉潔麗，楊臻瑞，高 翔，賴 瑞，趙 澤，汪唐順(299)

槲皮素對鎘致小鼠肝臟脂質代謝紊亂模型的保護效應··························································································································· 李自發(fā)，張 浩，任 萌，徐凱勇，胡明會，周苗苗，王可洲(305)

二甲雙胍對阿爾茨海默癥模型大鼠認知功能障礙及PI3K/Akt通路的影響···························································································································· 王百喬，林小茹，韓敏，劉 煜，唐超玲(313)

β-氨基丙腈聯(lián)合血管緊張素Ⅱ改良法建立小鼠主動脈夾層模型·································································································· 程玲霞，陳 琳，楊 帆，劉 英，陳睦虎，胡迎春，宋其泰，鐘 武(321)

高滲鹽水保護血腦屏障減輕腦出血大鼠腦水腫的相關機制研究··········· 第五飛虎，趙志靖，鄧毅恒(327)

MC38結腸癌小鼠腫瘤浸潤免疫細胞的動態(tài)變化············ 張波揚，陳煥鵬，余文蘭，劉忠華，黃朝峰(409)

CD137信號調控內皮細胞間質轉化促進小鼠心腦血管新生·········· 翁嘉懿，馬雪興，李 淵，孫康云(418)

咽立爽口含滴丸對慢性咽炎家兔免疫細胞亞群及NF-κB信號通路的影響······················································································································· 唐 燚，喻國凍，何星辰，王 佳，張 田(426)

多囊卵巢綜合征-胰島素抵抗大鼠子宮組織中PPARs異常表達與胰島素抵抗的關系································································································ 魏 巍，陳藝華，張秀智，冷義福，李 純，尹天曉(435)

基于糖尿病-腫瘤小鼠模型研究糖尿病對結直腸癌/乳腺癌進展及腸道菌群的影響························································································································· 王曉鈺,蔣升瑤,藺智兵,崔 立(469)

小鼠腹主動脈瘤模型的建立及組織學特征分析······································································································································ 夏聰聰,劉浩樂,魏盼盼,成大欣,胥寶會,劉恩岐,趙四海(480)

四氯化碳誘導急性肝損傷大鼠模型對心臟的影響···································································································································· 張麗麗,萬 鑫,冀菁荃,李 婷,范毅敏,李寶紅,田帥燕(486)

人源腫瘤異種移植動物模型在癌癥精準醫(yī)學研究中的應用······················ 宋偉杰,周 巖,牛瑞芳(493)

Rncat先天性白內障小鼠模型培育及初步應用····················································· 張 燕,燕順生(501)

卵巢早衰動物模型構建方法及比較研究進展······················································································································································· 李虹璇,李思慧,馮嘉欣,唐 凱,盧 蕊,韓絲銀(505)

糖尿病動物皮膚損傷模型制備要素和受試物數(shù)據(jù)的文獻分析······················································································································ 林江,駱 飛,劉 鵬,韓絲銀,陳振興,梁忠秀,蘭太進(515)

·技術與方法·

利用基質膠阻斷門靜脈建立改良ALPPS手術小鼠模型·················· 沈 皓，陳 瑤，沈 鋒，吳孟超(91)

大鼠尾椎間盤不同切片方式及染色方法的組織學觀察比較······················ 趙宇朋，周平輝，官建中(100)

大鼠血清葡萄糖測定分析的影響因素········································································································································ 李 紅，敬海明，林長纓，郭 婧，張 勐，張 超，高 珊，余儒洋(466)

2013—2020年7次實驗動物病原菌項目國際比對結果分析·············································································································· 邢 進，馮育芳，王 洪，張雪青，高 強，岳秉飛，付 瑞(521)

基于團體標準T/CALAS 21—2017的Wistar大鼠微衛(wèi)星DNA群體遺傳質量分析························································ 魏 杰，左 琴，王 洪，李 歡，周佳琪，光姣娜，范 濤，劉佐民，付 瑞，岳秉飛(528)

影響細菌人工染色體轉基因小鼠制備效率的因素分析······· 王芊芊，王 偉，劉 睿，劉 振，劉 沖(535)

大鼠氣管滴注方法的改良及效果評價······························ 余伊翔，曹珊珊，馮 怡，李嘉瑞，王 榮(543)

可視化核酸檢測技術RPA-LFD的研究和應用進展·································· 于靈芝，陶凌云，魏曉鋒(547)

·實驗動物管理·

實驗材料檢測在SPF級實驗小鼠質量控制中的應用····················································································································· 陳國元，康 康，李曉嫻，紀文韜，張金梅，馮延花，田倩瑩，吳寶金(61)

實驗動物健康碼管理的架構設計····································· 姜 鯤，湯逸雯，劉延濱，陳歷銘，湯宏斌(66)

人工繁育恒河猴的肺炎鏈球菌攜帶狀況調查及分析················································· 劉 雨，李艷艷，張 偉，楊鳳梅，劉 權，李詠潔，靳瑋華，段素琴，王俊斌，陳麗雄，徐鴻界，趙 遠，和占龍(259)

小鼠諾如病毒感染實驗小鼠的抗體變化規(guī)律分析··········································································································· 李曉波，付 瑞，王淑菁，李 威，王莎莎，黃宗文，秦 驍，王 吉，岳秉飛(343)

小鼠嗜肺巴斯德桿菌檢測方法優(yōu)化及感染小鼠的藥物凈化·········· 張 韜，崔 璨，馬貫中，張愛華(351)

病原微生物防控在實驗動物設施管理與生物安全控制中的作用探討······························································································································· 羅銀珠，閔凡貴，王 靜，何麗芳，潘金春(443)

醫(yī)學院校實驗動物及實驗室安全培訓的實踐探索··············· 宋國英，許燕，朱美霖，張宏偉，李 沛(450)

醫(yī)學實驗教學動物尸體二維碼信息管理系統(tǒng)建立的設想···· 金 悠，王晨晨，余上斌，羅雋宇，周順長(455)

高校實驗動物集中采購系統(tǒng)的建設與應用實踐：以首都醫(yī)科大學為例········································································································································· 劉曉楠，張 偉，孟 霞，盧 靜(459)

高校實驗動物管理流程信息化探索：以浙江大學為例······························· 陳曉娟,李 巍,汪 洌(554)

·實驗動物與精神醫(yī)學·

從腦胃ghrelin通路探討應激對大鼠食欲的影響···· 趙怡玲，高鵬飛，肖 茜，張 嵐，潘丹青，徐月妹(207)

·實驗動物與中醫(yī)藥·

痰熱清注射液的安全藥理學動物實驗評價······················································································································ 胡 俊，張小利，楊 春，陸錦遙，王 瓊，谷穎敏，謝家駿，張超超，田雪松(46)

竹節(jié)香附素A對肝缺血再灌注大鼠的保護作用機制······················ 李洪波，黃 銳，代 將，鐘振東(55)

苦參素對實驗性自身免疫性甲狀腺炎大鼠Th1/Th2細胞平衡及相關通路的影響······································································································································· 姚 婷，高 原，曾芳馨(244)

·實驗動物與安全性評價·

耐輻射奇球菌R1對大鼠的慢性毒性實驗·············································································································· 許 琴，王 瑋，董翔，李建瑛，是文輝，劉曉祿，劉愛中，馬 娜，宋來陽，劉江偉(333)

·實驗動物資源·

樹鼩脊髓微血管內皮細胞的分離培養(yǎng)及EV71感染實驗···· 施梅言，王 璇，王文廣，阮蕾穎，代解杰(148)

幾種常用免疫缺陷小鼠的血液學及血液淋巴細胞亞群的測定與比較分析·······································談小倩，瞿 偉，李 亮，錢 珍，顧堅忠，徐 平····································································· (155)

小鼠樹突狀細胞亞群分類及其比較研究進展···················································· 阮蕾穎，孫曉梅(174)

·實驗動物設施·

溶液式環(huán)境控制設備在實驗動物設施中的應用··············· 張 婷，陳亮亮，李海翔，黃發(fā)洲，蔡武凱(161)

兩種不同類型實驗動物屏障設施的氣流組織計算流體力學模擬技術分析···································································································································· 周 斌，趙 勇，汪亞兵，劉吉宏(252)

·教育培訓實踐·

醫(yī)院科研工作中開展實驗動物福利倫理教育的探索································ 余 飛，錢麗萍，沙莉莉(166)

基于互聯(lián)網交互平臺三明治教學法在醫(yī)學實驗動物學教學中的應用··················································································································· 魏 盛，耿希文，徐凱勇，胡明會，周苗苗，李自發(fā)(266)

·實驗動物產業(yè)與信息服務·

實驗動物電商平臺數(shù)據(jù)分析與對策建議················································· 溫金銀，陳 焰，李會萍(363)

·規(guī)范與指南·

學術研究實施與報告和醫(yī)學期刊編輯與發(fā)表的推薦規(guī)范（三）····················································································································· 國際醫(yī)學期刊編輯委員會(張俊彥，于笑天，汪 源，譯)(79)