妊娠糖尿病患者中應(yīng)用血清膽固醇、尿酸和糖化血紅蛋白檢測(cè)的價(jià)值

錢雅婷

[摘要] 目的 探討妊娠糖尿病患者中應(yīng)用血清膽固醇、尿酸和糖化血紅蛋白檢測(cè)的價(jià)值。方法 于2018年1月—2019年12月，將該院產(chǎn)科70例妊娠期糖尿病孕婦（觀察組）與70名健康孕婦（對(duì)照組）納入研究，測(cè)定孕婦血清膽固醇、尿酸、糖化血紅蛋白，比較兩組檢測(cè)結(jié)果，分析血清膽固醇、尿酸、糖化血紅蛋白與妊娠期糖尿病的相關(guān)性。 結(jié)果 總膽固醇、低密度脂蛋白膽固醇、尿酸、糖化血紅蛋白在觀察組中均高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05），高密度脂蛋白膽固醇在觀察組中低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）?？偰懝檀?、低密度脂蛋白膽固醇、尿酸、糖化血紅蛋白與妊娠糖尿病呈正相關(guān)，高密度脂蛋白膽固醇與妊娠期糖尿病呈負(fù)相關(guān)。結(jié)論 妊娠期糖尿病孕婦的血清膽固醇、尿酸、糖化血紅蛋白水平往往發(fā)生異常改變，臨床上可通過檢測(cè)血清膽固醇、尿酸、糖化血紅蛋白，在妊娠期糖尿病預(yù)測(cè)及治療中均可發(fā)揮良好的輔助指導(dǎo)作用。

[關(guān)鍵詞] 產(chǎn)科;妊娠期糖尿病膽固醇;尿酸;糖化血紅蛋白

[中圖分類號(hào)] R446.1? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1672-4062（2020）09（b）-0048-03

The Value of Serum Cholesterol， Uric Acid and Glycosylated Hemoglobin Detection in Patients with Gestational Diabetes

QIAN Ya-ting

Department of Laboratory Medicine， Quanzhou Maternal and Child Health Hospital（Children's Hospital）， Quanzhou， Fujian Province， 362000 China

[Abstract] Objective To explore the value of serum cholesterol， uric acid and glycosylated hemoglobin in patients with gestational diabetes. Methods From January 2018 to December 2019， 70 pregnant women with gestational diabetes （observation group） and 70 healthy pregnant women （control group） in the obstetric department of the hospital were included in the study. Serum cholesterol， uric acid， and glycosylated hemoglobin of pregnant women were measured and compared. The two groups of test results analyzed the correlation between serum cholesterol， uric acid， glycosylated hemoglobin and gestational diabetes. Results Total cholesterol， low-density lipoprotein cholesterol， uric acid， and glycosylated hemoglobin were higher in the observation group than in the control group，the difference was statistically significant（P<0.05）， and high-density lipoprotein cholesterol was lower in the observation group than in the control group，the difference was statistically significant（P<0.05）. Total cholesterol， low-density lipoprotein cholesterol， uric acid， glycosylated hemoglobin are positively correlated with gestational diabetes， and high-density lipoprotein cholesterol was negatively correlated with gestational diabetes. Conclusion The serum cholesterol， uric acid， and glycosylated hemoglobin levels of pregnant women with gestational diabetes often have abnormal changes. Clinically， the detection of serum cholesterol， uric acid， and glycosylated hemoglobin can play a good auxiliary guiding role in the prediction and treatment of gestational diabetes.

[Key words] Obstetrics; Gestational diabetes cholesterol; Uric acid; Glycosylated hemoglobin