• <tr id="yyy80"></tr>
  • <sup id="yyy80"></sup>
  • <tfoot id="yyy80"><noscript id="yyy80"></noscript></tfoot>
  • 99热精品在线国产_美女午夜性视频免费_国产精品国产高清国产av_av欧美777_自拍偷自拍亚洲精品老妇_亚洲熟女精品中文字幕_www日本黄色视频网_国产精品野战在线观看 ?

    Two-stage liver transplant for ruptured hepatic adenoma: A case report

    2019-03-21 11:34:38MarcSalhanickMalcolmMacConmaraMarkPedersenLafaineGrantChristineHwangJustinParekh
    World Journal of Hepatology 2019年2期

    Marc Salhanick, Malcolm P MacConmara, Mark R Pedersen, Lafaine Grant, Christine S Hwang, Justin R Parekh

    Abstract BACKGROUND Only one case of liver transplantation for hepatic adenoma has previously been reported for patients with rupture and uncontrolled hemorrhage. We present the case of a massive ruptured hepatic adenoma with persistent hemorrhagic shock and toxic liver syndrome which resulted in a two-stage liver transplantation. This is the first case of a two-stage liver transplantation performed for a ruptured hepatic adenoma.CASE SUMMARY A 23 years old African American female with a history of pre-diabetes and oral contraceptive presented to an outside facility complaining of right-sided chest pain and emesis for one day. She was found to be in hemorrhagic shock due to a massive ruptured hepatic hepatic adenoma. She underwent repeated embolizations with interventional radiology with ongoing hemorrhage and the development of renal failure, hepatic failure, and hemodynamic instability,known as toxic liver syndrome. In the setting of uncontrolled hemorrhage and toxic liver syndrome, a hepatectomy with porto-caval anastomosis was performed with liver transplantation 15 h later. She tolerated the anhepatic stage well, and has done well over one year later.CONCLUSION When toxic liver syndrome is recognized, liver transplantation with or without hepatectomy should be considered before the patient becomes unstable.

    Key words: Hepatic adenoma; Toxic liver syndrome; Two-stage liver transplantation;Hepatectomy; Ruptured adenoma; Case report

    INTRODUCTION

    Hepatic adenomas are an uncommon solid tumor of the liver with an estimated incidence of 3-4 per 100000 women[1]. Hemorrhagic rupture occurs in 10%-31% of patients with hepatic adenomas, with treatment options including embolization and surgical resection with good outcomes[2,3].

    One case of liver transplantation has previously been reported for patients with rupture and uncontrolled hemorrhage from a hepatic adenoma[4]. We present the case of a massive ruptured hepatic adenoma with persistent hemorrhagic shock and toxic liver syndrome which resulted in a two-stage liver transplantation. This is the first case of a two-stage liver transplantation performed for a ruptured hepatic adenoma.

    CASE PRESENTATION

    Chief complaints

    A 23 year old African American female with a history of pre-diabetes and oral contraceptive use since age 11, presented to an outside facility complaining of rightupper-quadrant pain, generalized weakness, and emesis for one day. She had been in her usual state of health until that morning when she experiences the acute onset of stabbing right-upper-quadrant pain that radiated to her chest. She quickly felt nauseous and had several episodes of non-bloody emesis.

    History of past illness

    She had a past medical history significant for pre-diabetes and oral contraceptive use,but otherwise had no other medical problems and took no other medications.

    Personal and family history

    She had no history of alcohol, tobacco, or drug abuse, and no family history of liver disease.

    Physical examination upon admission

    Her initial physical exam was remarkable for pallor. She was afebrile with an initial blood pressure of 96/52 mmHg and a heart rate of 126 beats per minute. Her abdominal exam was notable for right-upper-quadrant tenderness and fullness. Her cardiopulmonary exam was normal except for tachycardia. Initial labs revealed a hemoglobin 8.7 gm/dL, platelets 396 × 109/L, lactic acid 5.6 mmol/L, alanine aminotransferase (ALT) 100 IU/L, aspartate aminotransferase (AST) 166 IU/L, total bilirubin 0.3 mg/dL, creatinine 1.30 mg/dL, blood urea nitrogen 13 mg/dL, and bicarbonate 18 mEq/L. A urinary pregnancy test was negative.

    Imaging examinations

    Initial imaging would include a CT of the abdomen and pelvis with contrast demonstrated a large 22 cm x 15 cm heterogenous, hypoattenuating mass encompassing nearly the entire liver. The mass demonstrated hypervascularity along the border and hyperattenuating areas, suggesting a large hemorrhagic liver mass with active hemorrhage. There was no rupture of the liver and no perihepatic,subcapsular hematoma (Figure 1). She was given preliminary diagnosis of hemorrhagic shock due to this hemorrhagic liver mass and was transferred to a second hospital for interventional radiology.

    On arrival, her hemoglobin was 9.6 gm/dL after transfusion of 6 units of packed red blood cells. She underwent gel foam embolization of the right hepatic artery.However, throughout the evening she required ongoing blood transfusions. A repeat CT scan demonstrated enlargement of the intrahepatic hematoma with new intraperitoneal fluid, retroperitoneal fluid, and bilateral pleural effusion concerning for ongoing hemorrhage. She was then taken back for a mesenteric angiogram with embolization of the middle hepatic artery and repeat embolization of the right hepatic artery. During this period, her ALT increased to 1023 IU/L, AST 2287 IU/L, bilirubin 3.2 mg/dL, alkaline phosphatase 506 IU/L, and lactic acid 8.3 mmol/L. She had ongoing hemodynamic instability and anuric kidney injury (creatinine 1.73 mg/dL).She was then transferred to our facility.

    FINAL DIAGNOSIS

    Here, an angiogram demonstrated active extravasation from the liver lesion (Figure 2). Repeat embolization of the entire right hepatic artery was performed. Despite these interventions and additional resuscitation, she had progressive acidosis, increasing pressor requirement, and worsening of her bilirubin, INR, and lactate (Table 1). With this rapidly deteriorating hepatic function with hemodynamic instability and renal failure, she was diagnosed with toxic liver syndrome.

    TREATMENT

    She was then taken to the operating room where the liver was found to have a rupture extending across the entire right lobe into segment 4 anteriorly, as well as a separate rupture posteriorly. Both fractures were at least 4 cm deep and more than 10 cm long with active rupture into the abdomen (Figure 3). Her right lobe and most of the left had been almost entirely replaced by coagulated blood inside of the adenoma. There was significant compressive effect of the enlarged liver on the portal vein and hepatic artery. Only a small lateral portion of segments II and III was uninvolved.

    Given the size of the mass with compressive effect on adjacent vasculature, ongoing bleeding during the operation, and the ischemic injury to the remaining liver, it was decided that total hepatectomy followed by transplant would be her best chance at survival. Resection was not thought to be viable as only a small remnant of uninvolved liver remained, and this small portion was felt to already be heavily injured by preceding ischemia. The liver was then dissected off the cava. The hepatic vein stumps were oversewn and a porto-caval shunt created. Final pathology demonstrated a liver size of 34.5 cm × 22.5 cm × 8.5 cm with a red-tan hepatic adenoma measuring 30 cm × 22.5 cm × 8.5 cm. Coagulative necrosis was noted throughout tumor with intravascular foreign material consistent with embolization.The remnant liver tissue demonstrated massive necrosis with only a few remaining periportal hepatocytes.

    After hepatectomy, her hemodynamics stabilized and her urine output increased.She underwent urgent liver transplant evaluation and was listed as status 1,anhepatic. She was maintained intubated on continuous venovenous hemodialysis with target sodium 145-150 mEq/L, a fresh frozen plasma drip, a 50% dextrose solution drip, empiric antibiotics, frequent calcium checks, and elevation of the head of bed. She required minimal sedation during this period with an intermittent low dose fentanyl drip. She was anhepatic for a total of 15 h before going back to the operating room for an orthotopic liver transplantation. A standard piggyback transplant was performed and a supra-celiac aortic conduit was created given the celiac dissection that had been noted earlier.

    OUTCOME AND FOLLOW-UP

    Figure 1 CT scan prior to interventions. A CT of the abdomen and pelvis with contrast demonstrated a large 22 cm × 15 cm heterogenous, hypoattenuating mass encompassing nearly the entire liver. The mass demonstrated hypervascularity along the border and hyperattenuating areas, suggesting a large hemorrhagic liver mass with active hemorrhage.

    She tolerated the procedure well, and had one take-back surgery due to elevated liver function tests with findings of increased resistive indices on ultrasound.Intraoperatively, the vessels were found to be intact with some compression from abdominal wall edema which did not require any intervention other than additional volume removal. Her recovery was otherwise unremarkable. She was extubated on post-transplant day 4. She was discharged from the hospital on post-transplant day 8.

    DISCUSSION

    When adenomas rupture, they are managed with resuscitation to achieve hemodynamic stability and nonsurgical modalities such as embolization to control bleeding[5,6]. When conservative measure fail, partial hepatectomy or packing of the liver may be used to control the hemorrhage[3,7]. In rare cases, liver transplantation may be considered[4]. To date, 67 patients have been transplanted with hepatic adenoma as the primary diagnosis according to the Organ Procurement and Transplantation Network (exact indications are not specified, but presumably due to size, malignant transformation, multifocality, or hemorrhage)[8]. Only one case of liver transplant for a hemorrhagic hepatic adenoma has been reported in the literature[4].

    We present the case of a massive ruptured hepatic adenoma that would ultimately require a hepatectomy prior to liver transplant to manage. While the patient suffered a significant hemorrhage with rupture of her liver, the degree of hepatic and physiologic dysfunction she experienced was out of proportion solely to the degree of hemorrhage that she experienced. It is unusual for otherwise healthy patients to have such marked liver dysfunction, even in the setting of prolonged hypotension[9].However, with the mass effect of a ruptures liver on the perihepatic vasculature,almost complete replacement of the hepatic parenchyma by adenoma and hematoma,and further damage from hemorrhagic shock and three embolization procedures, her liver parenchyma started to necrose and resulted in toxic liver syndrome.

    Ringe et al[10]first coined the term toxic liver syndrome to describe patients with a non-functioning liver associated with hemodynamic instability and renal failure. The condition, though rare, is important to recognize. A recent case series from Kaltenborn et al[11]found that the cause for mortality in similar patients is not hemorrhage, which can usually be halted with packing or ligation of the porta, rather the liver necrosis and subsequent toxic liver syndrome. Cessation of hemorrhage would not have rescued this patient. In this case, the segment of remaining liver was too small to be viable, and the ongoing egress of necrotic byproducts from any retained liver would have continued to propagate her unstable state. Total hepatectomy was necessary to control hemorrhage and to relieve the physiologic sequelae of toxic liver syndrome. As a result, post-hepatectomy her heart rate normalized, her urine output tripled, and her vasoactive medications were stopped.

    The use of a hepatectomy with a portocaval shunt prior to liver transplant is sometimes referred to as a two-stage liver transplant and can temporize patient awaiting an organ to transplant. Two-stage liver transplantation was first reported in1988 and is used as a last resort for patients who are unstable due to exsanguinating hemorrhage (from trauma or an irreparable laceration due to a ruptured hepatic adenoma) or overwhelming inflammation (such as from primary graft non-function or acute liver failure)[12-14]. While early mortality for the two-stage liver transplant was as high as 60%-76% within the first year[10,15,16], the mortality in the last decade has been reported to be as low as 24% in some series[12-14].

    Table 1 Peri-transplant hemodynamics and labs

    Our patient tolerated the hepatectomy remarkably well. She had rapid hemodynamic stabilization and improvement in her urine output. During this stage,other consequences of the anhepatic state were carefully monitored. Hypoglycemia,due to a lack of hepatic gluconeogenesis, was controlled with a 50% dextrose drip.Hypocalcemia, a consequence of multiple citrate-containing blood transfusion combined with the inability to metabolize citrate, was carefully monitored and corrected[15]. Volume status and acid-base balance was managed with continuous veno-venous hemodialysis. Increased intracranial pressure was avoided by elevation of the head of the bed and maintenance of mild hypernatremia. She was transplanted 15 hours later, and was discharged within approximately one week of liver transplantation. At the time of submission, the patient continues to do well over a year from transplant and has not had to be re-hospitalized.

    This case describes a rare and dramatic complication of a hepatic adenoma that resulted in both massive hemorrhage and liver dysfunction which could only be treated with hepatectomy. Recognition of toxic liver syndrome is essential when dealing with patients who suffer massive liver necrosis in attempts to control bleeding. Though embolization to control bleeding is an important first step,ultimately these patients will not be definitively managed by embolization procedures. Early consideration should be given to liver transplantation with or without hepatectomy before the patient becomes too unstable to proceed.

    CONCLUSION

    Figure 2 Mesenteric angiogram prior to transplant. Mesenteric angiogram demonstrating a large right hepatic lobe with multiple areas of abnormal contrast accumulation indicative of ongoing hemorrhage. Gelfoam embolization of the right hepatic artery was performed.

    Toxic liver syndrome describes patients with a non-functioning liver associated with hemodynamic instability and renal failure. Mortality in these patients are not from the hemorrhage itself, rather the liver necrosis and subsequent toxic liver syndrome. A two-stage liver transplantation, or the use of a hepatectomy with a portocaval shunt prior to liver transplant, should be considered in patients with toxic liver syndrome.Anhepatic patients require careful management of hypoglycemia, hypocalcemia,volume status, acid-base balance, and intracranial pressure, among other parameters.Further research is needed to determine the optimal management of anheptic patients and ways to identify the point when hepatectomy would be most useful in patients developing toxic liver syndrome.

    Figure 3 Explanted liver. Explanted liver, measuring 34.5 cm × 22.5 cm × 8.5 cm, with a large surface disruption with adenomatous tissue and significant adherent clot.

    国产伦精品一区二区三区视频9| 美女内射精品一级片tv| 国产视频内射| 亚洲av中文字字幕乱码综合| 日本五十路高清| 搡女人真爽免费视频火全软件| 99久久精品热视频| 日本与韩国留学比较| 久久鲁丝午夜福利片| 美女被艹到高潮喷水动态| 国产精品久久电影中文字幕| 精品久久久久久成人av| 国产亚洲欧美98| 久99久视频精品免费| 国内精品宾馆在线| 久久久久网色| 毛片女人毛片| 午夜免费激情av| 国产亚洲精品久久久com| 亚洲最大成人手机在线| 麻豆国产av国片精品| 三级毛片av免费| 亚洲成a人片在线一区二区| 91精品国产九色| 国产成人精品一,二区 | 免费电影在线观看免费观看| 日韩高清综合在线| 日韩大尺度精品在线看网址| 亚洲国产高清在线一区二区三| 日韩精品有码人妻一区| 一边摸一边抽搐一进一小说| 丝袜喷水一区| av在线蜜桃| 国产精品国产三级国产av玫瑰| 99国产精品一区二区蜜桃av| 别揉我奶头 嗯啊视频| 成人高潮视频无遮挡免费网站| 欧美日本亚洲视频在线播放| 免费大片18禁| 特大巨黑吊av在线直播| 91狼人影院| 亚洲精品日韩在线中文字幕 | 美女被艹到高潮喷水动态| 天堂中文最新版在线下载 | 国产69精品久久久久777片| 小蜜桃在线观看免费完整版高清| 亚洲精品日韩在线中文字幕 | 国语自产精品视频在线第100页| av免费观看日本| 18禁在线播放成人免费| 人妻少妇偷人精品九色| 欧美一级a爱片免费观看看| 久久久久国产网址| 国产乱人视频| 亚洲精品粉嫩美女一区| 精品欧美国产一区二区三| 尤物成人国产欧美一区二区三区| 国产白丝娇喘喷水9色精品| 久久国产乱子免费精品| 搡老妇女老女人老熟妇| 麻豆av噜噜一区二区三区| 国产精品不卡视频一区二区| 国产乱人视频| 哪里可以看免费的av片| 男人的好看免费观看在线视频| 亚洲欧美日韩高清专用| 十八禁国产超污无遮挡网站| 一级毛片aaaaaa免费看小| 成年版毛片免费区| 26uuu在线亚洲综合色| 精品免费久久久久久久清纯| 极品教师在线视频| 狂野欧美白嫩少妇大欣赏| 亚洲美女搞黄在线观看| 少妇熟女aⅴ在线视频| 91av网一区二区| 天美传媒精品一区二区| 一级av片app| 一个人看视频在线观看www免费| 国产午夜精品久久久久久一区二区三区| 成人漫画全彩无遮挡| 日本撒尿小便嘘嘘汇集6| 国产精品不卡视频一区二区| 国产极品天堂在线| 嫩草影院精品99| 国产精品一区www在线观看| 99精品在免费线老司机午夜| 一进一出抽搐gif免费好疼| 国产男人的电影天堂91| 99久国产av精品国产电影| 日本一本二区三区精品| 亚洲电影在线观看av| 久久久久久久久久黄片| 一本一本综合久久| 久久久a久久爽久久v久久| 寂寞人妻少妇视频99o| 国产男人的电影天堂91| 成人av在线播放网站| 国产午夜精品一二区理论片| 午夜福利高清视频| 国产精品日韩av在线免费观看| 少妇熟女欧美另类| 亚洲欧美成人精品一区二区| 日韩欧美精品v在线| 日本爱情动作片www.在线观看| 欧美成人精品欧美一级黄| 大香蕉久久网| 九九久久精品国产亚洲av麻豆| 一边摸一边抽搐一进一小说| 高清毛片免费看| 女同久久另类99精品国产91| 亚洲国产欧洲综合997久久,| 亚洲欧美中文字幕日韩二区| 午夜视频国产福利| 亚洲自拍偷在线| 欧美性感艳星| 亚洲欧美精品综合久久99| 婷婷亚洲欧美| 日日撸夜夜添| 午夜福利视频1000在线观看| 午夜精品一区二区三区免费看| 国产高潮美女av| 久久精品综合一区二区三区| 少妇熟女欧美另类| 日本熟妇午夜| 草草在线视频免费看| 18禁裸乳无遮挡免费网站照片| 国产成人a区在线观看| 亚洲成人久久性| 久久久精品94久久精品| 国产日本99.免费观看| 国产免费男女视频| 国内揄拍国产精品人妻在线| 成人无遮挡网站| 黄色欧美视频在线观看| 亚洲精品日韩在线中文字幕 | 夜夜看夜夜爽夜夜摸| 麻豆国产97在线/欧美| 秋霞在线观看毛片| 人妻制服诱惑在线中文字幕| 国产精品无大码| 九色成人免费人妻av| 成人午夜高清在线视频| 在线免费十八禁| 国产色爽女视频免费观看| 日本-黄色视频高清免费观看| 菩萨蛮人人尽说江南好唐韦庄 | 草草在线视频免费看| 一边亲一边摸免费视频| 欧美成人a在线观看| 国产麻豆成人av免费视频| 欧美另类亚洲清纯唯美| 国产探花在线观看一区二区| 少妇高潮的动态图| 一级黄色大片毛片| 亚洲欧美精品专区久久| 2021天堂中文幕一二区在线观| 成人国产麻豆网| 狂野欧美激情性xxxx在线观看| 嫩草影院入口| 中文字幕精品亚洲无线码一区| 亚洲人成网站在线播| 美女被艹到高潮喷水动态| 亚洲欧美日韩无卡精品| 成人无遮挡网站| 免费一级毛片在线播放高清视频| 亚洲国产精品sss在线观看| 成人无遮挡网站| 99久久精品一区二区三区| 欧美性猛交黑人性爽| 99热这里只有是精品在线观看| 网址你懂的国产日韩在线| 亚洲精品色激情综合| 99在线视频只有这里精品首页| 97超碰精品成人国产| www日本黄色视频网| 毛片女人毛片| 国产伦理片在线播放av一区 | 麻豆乱淫一区二区| 国内精品一区二区在线观看| 男女做爰动态图高潮gif福利片| 久久久色成人| 欧美+日韩+精品| 国产蜜桃级精品一区二区三区| 麻豆国产av国片精品| 亚洲在久久综合| 黑人高潮一二区| 非洲黑人性xxxx精品又粗又长| 免费无遮挡裸体视频| 亚洲av成人av| 欧美丝袜亚洲另类| 在线观看66精品国产| 床上黄色一级片| 人妻久久中文字幕网| 成年女人看的毛片在线观看| 最近视频中文字幕2019在线8| 精品久久久久久成人av| 午夜福利高清视频| 亚洲aⅴ乱码一区二区在线播放| 日韩视频在线欧美| 成人三级黄色视频| 一本久久中文字幕| 国产伦理片在线播放av一区 | 午夜福利成人在线免费观看| 久久精品91蜜桃| 嫩草影院精品99| 精品久久久久久久久久久久久| 22中文网久久字幕| 两个人视频免费观看高清| 老师上课跳d突然被开到最大视频| 国产乱人视频| 性插视频无遮挡在线免费观看| 精品国内亚洲2022精品成人| 欧美日韩精品成人综合77777| 男人和女人高潮做爰伦理| 日日摸夜夜添夜夜添av毛片| 菩萨蛮人人尽说江南好唐韦庄 | 免费黄网站久久成人精品| 我的老师免费观看完整版| 69人妻影院| 日本一本二区三区精品| 国产免费一级a男人的天堂| 深夜精品福利| 能在线免费看毛片的网站| 观看免费一级毛片| 中文亚洲av片在线观看爽| 国产伦精品一区二区三区视频9| 午夜福利在线观看吧| 久久久精品大字幕| 欧美日韩综合久久久久久| 亚洲欧洲国产日韩| 一级毛片我不卡| 又爽又黄a免费视频| 在线a可以看的网站| 婷婷六月久久综合丁香| 日日干狠狠操夜夜爽| 久久精品夜色国产| 丝袜喷水一区| 三级国产精品欧美在线观看| 国产精品久久久久久亚洲av鲁大| 麻豆国产97在线/欧美| 18禁裸乳无遮挡免费网站照片| 久久精品国产鲁丝片午夜精品| 伦理电影大哥的女人| 深夜a级毛片| 久久久久久国产a免费观看| 麻豆成人午夜福利视频| 国产av一区在线观看免费| 在线观看66精品国产| 久久精品国产自在天天线| 精品人妻熟女av久视频| 一级黄色大片毛片| 观看美女的网站| 亚洲欧美日韩高清在线视频| 国产不卡一卡二| 少妇人妻精品综合一区二区 | 欧美一区二区亚洲| 国产成人a区在线观看| 色噜噜av男人的天堂激情| 国产中年淑女户外野战色| 在线观看免费视频日本深夜| 一级二级三级毛片免费看| 久久人人精品亚洲av| 成人无遮挡网站| 精品少妇黑人巨大在线播放 | 国产真实乱freesex| 变态另类成人亚洲欧美熟女| 观看美女的网站| 日韩一区二区视频免费看| avwww免费| 午夜激情福利司机影院| 亚洲第一区二区三区不卡| 亚洲七黄色美女视频| 看黄色毛片网站| 丰满人妻一区二区三区视频av| 男人狂女人下面高潮的视频| 国产精品综合久久久久久久免费| 久久午夜福利片| 伊人久久精品亚洲午夜| or卡值多少钱| 亚洲在线自拍视频| 亚洲欧美成人综合另类久久久 | 波多野结衣巨乳人妻| 亚洲av男天堂| 中出人妻视频一区二区| 久久热精品热| 久久九九热精品免费| 国产精品1区2区在线观看.| 综合色丁香网| 国产激情偷乱视频一区二区| 国产高清激情床上av| 精品无人区乱码1区二区| 在线观看免费视频日本深夜| 国产黄色小视频在线观看| 看黄色毛片网站| 国产亚洲91精品色在线| 亚洲精品乱码久久久v下载方式| 亚洲欧美精品专区久久| 国产美女午夜福利| 国产成人精品久久久久久| 97热精品久久久久久| 久久精品国产亚洲av涩爱 | 国产毛片a区久久久久| 青春草亚洲视频在线观看| 国产色婷婷99| 色吧在线观看| 别揉我奶头 嗯啊视频| 婷婷色综合大香蕉| 99热这里只有是精品在线观看| 国产爱豆传媒在线观看| 午夜福利视频1000在线观看| 波野结衣二区三区在线| 亚洲av第一区精品v没综合| 麻豆一二三区av精品| 久久精品夜夜夜夜夜久久蜜豆| 桃色一区二区三区在线观看| 午夜福利高清视频| 好男人视频免费观看在线| 国产av麻豆久久久久久久| 久久久久久伊人网av| 精品99又大又爽又粗少妇毛片| 亚洲国产精品sss在线观看| 麻豆乱淫一区二区| 大型黄色视频在线免费观看| 国产亚洲精品久久久com| 日本成人三级电影网站| 夜夜爽天天搞| 色5月婷婷丁香| 亚洲熟妇中文字幕五十中出| 老女人水多毛片| 精品国产三级普通话版| 成人二区视频| 久久99蜜桃精品久久| 可以在线观看的亚洲视频| 插逼视频在线观看| 久久韩国三级中文字幕| www.av在线官网国产| 天美传媒精品一区二区| 国产午夜精品论理片| 久久久精品94久久精品| 中文字幕久久专区| 97超视频在线观看视频| 亚洲国产精品国产精品| 婷婷六月久久综合丁香| 内地一区二区视频在线| 国产真实伦视频高清在线观看| a级毛色黄片| 久久热精品热| 熟女人妻精品中文字幕| 91久久精品电影网| 久久九九热精品免费| 亚洲国产高清在线一区二区三| 午夜老司机福利剧场| 在线a可以看的网站| 精品久久久久久久末码| 少妇高潮的动态图| 欧美在线一区亚洲| 国产精品一区二区三区四区免费观看| 一夜夜www| 亚洲无线观看免费| 深爱激情五月婷婷| 在线播放无遮挡| 国产视频首页在线观看| 看黄色毛片网站| a级毛片免费高清观看在线播放| 免费一级毛片在线播放高清视频| 精品久久国产蜜桃| 99精品在免费线老司机午夜| 精品久久久久久久久av| 免费观看精品视频网站| 一边亲一边摸免费视频| 99热精品在线国产| 麻豆国产97在线/欧美| av专区在线播放| 少妇的逼好多水| 欧美潮喷喷水| 久久久久久久午夜电影| 99久久精品一区二区三区| 国产一区二区亚洲精品在线观看| 国产在线男女| 一级毛片电影观看 | 熟妇人妻久久中文字幕3abv| 偷拍熟女少妇极品色| 久久久久久久久久成人| 青青草视频在线视频观看| kizo精华| 一级毛片久久久久久久久女| 国产伦一二天堂av在线观看| 国产黄色小视频在线观看| 成人高潮视频无遮挡免费网站| 亚洲欧美日韩卡通动漫| 国语自产精品视频在线第100页| 嫩草影院入口| 熟女电影av网| 午夜免费激情av| 亚洲中文字幕一区二区三区有码在线看| 美女cb高潮喷水在线观看| 在线天堂最新版资源| 亚洲四区av| 日本黄大片高清| 国产人妻一区二区三区在| 久久精品人妻少妇| 久久99热6这里只有精品| 日韩人妻高清精品专区| 国模一区二区三区四区视频| 亚洲欧美成人精品一区二区| 97超视频在线观看视频| 日本黄色片子视频| 成人毛片a级毛片在线播放| 插阴视频在线观看视频| 白带黄色成豆腐渣| 综合色丁香网| 日韩在线高清观看一区二区三区| 精品国产三级普通话版| 热99re8久久精品国产| 婷婷亚洲欧美| 国产国拍精品亚洲av在线观看| 内地一区二区视频在线| 国产不卡一卡二| 直男gayav资源| 亚洲综合色惰| 国产色爽女视频免费观看| 久久人人爽人人爽人人片va| 国产伦精品一区二区三区四那| 一级毛片电影观看 | 变态另类成人亚洲欧美熟女| 亚洲最大成人手机在线| 午夜福利高清视频| 国产精品一二三区在线看| 亚洲成人精品中文字幕电影| 国产精品蜜桃在线观看 | 久久草成人影院| 热99在线观看视频| 午夜久久久久精精品| 久久人人爽人人爽人人片va| 国产精品人妻久久久久久| 深爱激情五月婷婷| 色综合色国产| 高清毛片免费观看视频网站| 身体一侧抽搐| 美女 人体艺术 gogo| 黄片无遮挡物在线观看| 免费黄网站久久成人精品| 美女黄网站色视频| 国产激情偷乱视频一区二区| 综合色丁香网| 变态另类成人亚洲欧美熟女| 老司机影院成人| 中文字幕av成人在线电影| 日韩一区二区三区影片| 91av网一区二区| 久久精品国产鲁丝片午夜精品| 亚洲国产欧美在线一区| 赤兔流量卡办理| 校园人妻丝袜中文字幕| 人人妻人人澡人人爽人人夜夜 | 日韩三级伦理在线观看| 亚洲丝袜综合中文字幕| 我要搜黄色片| 三级男女做爰猛烈吃奶摸视频| 日韩亚洲欧美综合| 久久99精品国语久久久| 亚洲av不卡在线观看| 色吧在线观看| 国产在线男女| av在线播放精品| 在线观看免费视频日本深夜| 久99久视频精品免费| 亚洲自拍偷在线| 色尼玛亚洲综合影院| 深夜精品福利| 国产亚洲精品av在线| 卡戴珊不雅视频在线播放| 精品熟女少妇av免费看| 中文字幕精品亚洲无线码一区| av国产免费在线观看| 国产在视频线在精品| 精品久久国产蜜桃| 不卡视频在线观看欧美| 亚洲精品国产av成人精品| 国产精品三级大全| 日韩成人伦理影院| 国产精品久久久久久av不卡| 日韩欧美 国产精品| a级毛色黄片| 亚洲欧美成人综合另类久久久 | 国产高潮美女av| 欧美3d第一页| 亚洲一级一片aⅴ在线观看| 亚洲丝袜综合中文字幕| 日日干狠狠操夜夜爽| 久久精品91蜜桃| 久久精品国产亚洲网站| 成人国产麻豆网| 亚洲三级黄色毛片| 青青草视频在线视频观看| 成人亚洲欧美一区二区av| 久久久国产成人免费| 国产精品福利在线免费观看| 国产在视频线在精品| 九九热线精品视视频播放| 少妇高潮的动态图| 国产真实乱freesex| 97人妻精品一区二区三区麻豆| 国产 一区 欧美 日韩| 噜噜噜噜噜久久久久久91| 九草在线视频观看| 国产片特级美女逼逼视频| 日本五十路高清| 亚洲国产精品国产精品| 91久久精品国产一区二区三区| 97在线视频观看| 天天一区二区日本电影三级| 美女cb高潮喷水在线观看| av天堂在线播放| 国产av一区在线观看免费| 欧美一区二区国产精品久久精品| 国产白丝娇喘喷水9色精品| 一本一本综合久久| 91av网一区二区| 天堂网av新在线| 久久久精品94久久精品| 黄色一级大片看看| 成人性生交大片免费视频hd| 五月伊人婷婷丁香| 联通29元200g的流量卡| 一夜夜www| 色哟哟哟哟哟哟| 国产精品久久久久久久久免| 亚州av有码| 国产精品不卡视频一区二区| 99riav亚洲国产免费| 欧美+亚洲+日韩+国产| 日本在线视频免费播放| 狂野欧美激情性xxxx在线观看| 国产精品一区二区在线观看99 | 97在线视频观看| 免费无遮挡裸体视频| 日韩 亚洲 欧美在线| 婷婷六月久久综合丁香| 在线国产一区二区在线| 六月丁香七月| 国产极品天堂在线| 最近最新中文字幕大全电影3| 一级二级三级毛片免费看| 高清午夜精品一区二区三区 | 精华霜和精华液先用哪个| 日韩视频在线欧美| 日日摸夜夜添夜夜爱| 22中文网久久字幕| 直男gayav资源| 中文字幕熟女人妻在线| 一级黄色大片毛片| 久久99热6这里只有精品| 一本—道久久a久久精品蜜桃钙片 精品乱码久久久久久99久播 | 哪个播放器可以免费观看大片| 亚洲在线自拍视频| 国产高清有码在线观看视频| 一区二区三区高清视频在线| 午夜精品国产一区二区电影 | 中文字幕人妻熟人妻熟丝袜美| 久久久久久大精品| 国产精品一区二区在线观看99 | 免费大片18禁| 色哟哟哟哟哟哟| 亚洲av电影不卡..在线观看| 色综合站精品国产| 黄色日韩在线| 桃色一区二区三区在线观看| 亚洲自偷自拍三级| 黄色一级大片看看| 午夜激情福利司机影院| 99久久中文字幕三级久久日本| 国产午夜精品论理片| 老司机影院成人| 日韩精品有码人妻一区| 人人妻人人看人人澡| 成人无遮挡网站| 91aial.com中文字幕在线观看| 日韩视频在线欧美| 99久久无色码亚洲精品果冻| av天堂在线播放| 精品久久久久久久久久免费视频| 女人十人毛片免费观看3o分钟| 日韩一本色道免费dvd| av黄色大香蕉| 精品免费久久久久久久清纯| 精品人妻偷拍中文字幕| 别揉我奶头 嗯啊视频| 18禁在线播放成人免费| 悠悠久久av| 国产精品永久免费网站| 青青草视频在线视频观看| 亚洲成人久久性| 国内久久婷婷六月综合欲色啪| 国产精品女同一区二区软件| 12—13女人毛片做爰片一| 国产精品永久免费网站| 欧美日韩乱码在线| 在线观看av片永久免费下载| 乱码一卡2卡4卡精品| 91在线精品国自产拍蜜月| 男女啪啪激烈高潮av片| 国产色爽女视频免费观看| 岛国在线免费视频观看| 久久热精品热| 久久久a久久爽久久v久久| 亚洲欧美日韩卡通动漫| 99国产极品粉嫩在线观看| 欧美一级a爱片免费观看看| 国产精品久久久久久av不卡| 亚洲乱码一区二区免费版| 可以在线观看毛片的网站| 国产精品久久视频播放| 美女大奶头视频|