高危剖宮產(chǎn)孕婦產(chǎn)后出血中應(yīng)用欣母沛防治的 療效探討

狄建英

[摘要] 目的 探討應(yīng)用欣母沛在高危剖宮產(chǎn)孕婦產(chǎn)后出血中的療效。方法 研究對(duì)象為方便選取2017年2月—2018年2月在該院接受剖宮產(chǎn)的80例高危孕婦，采取隨機(jī)數(shù)字表法將其分為對(duì)照組與研究組，每組40例。對(duì)照組給予縮宮素對(duì)孕婦產(chǎn)后出血進(jìn)行預(yù)防，同時(shí)聯(lián)合應(yīng)用卡孕栓直腸給藥。研究組給予欣母沛對(duì)孕婦產(chǎn)后出血進(jìn)行預(yù)防，對(duì)兩組孕婦的產(chǎn)后出血量、術(shù)中術(shù)后輸血、宮紗條及球囊使用、術(shù)后子宮恢復(fù)等臨床指標(biāo)進(jìn)行對(duì)比分析。結(jié)果 產(chǎn)后出血量對(duì)比：研究組孕婦術(shù)中出血量為﹙102.33±19.98﹚mL、產(chǎn)后2 h出血量為﹙207.62±65.14﹚mL、產(chǎn)后24 h出血量為﹙40.45±32.64﹚mL;對(duì)照組孕婦術(shù)中出血量為﹙234.15±26.43﹚mL、產(chǎn)后2 h出血量為﹙321.09±80.42﹚mL、產(chǎn)后24 h出血量為﹙84.12±50.07﹚mL;研究組孕婦術(shù)中出血量、產(chǎn)后2 h出血量以及產(chǎn)后24 h出血量均顯著低于對(duì)照組（t=43.258、10.369、7.011，P=0.001、0.002、0.001）。研究組術(shù)中術(shù)后輸血、宮紗條使用、球囊使用、術(shù)后子宮恢復(fù)等各項(xiàng)臨床指標(biāo)均明顯優(yōu)于對(duì)照組（χ2=4.682、4.756、4.633、8.641，P=0.019、0.024、0.027、0.033）。結(jié)論 高危剖宮產(chǎn)孕婦應(yīng)用欣母沛可對(duì)產(chǎn)后出血起到良好的防治作用，值得臨床加大研究并推廣采用。

[關(guān)鍵詞] 高危剖宮產(chǎn);產(chǎn)后出血;欣母沛;防治療效

[中圖分類號(hào)] R714? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-0742（2019）11（c）-0110-03

[Abstract] ObjectiveTo explore the efficacy of hemabate in the postpartum hemorrhage of high-risk cesarean section pregnant women.Methods The study subjects were 80 high-risk pregnant women who underwent cesarean section in our hospital from February 2017 to February 2018. They were convenient selection randomly divided into a control group and a study group， 40 cases each group. The control group was given oxytocin to prevent postpartum hemorrhage in pregnant women， and combined with rectal administration. The research group gave hemabate prevention of postpartum hemorrhage in pregnant women. The clinical indexes of postpartum hemorrhage， intraoperative blood transfusion， intrauterine strip and balloon use， and postoperative uterine recovery were compared. Results Comparison of postpartum hemorrhage： the intraoperative blood loss of the pregnant women in the study group was﹙102.33±19.98﹚mL， the bleeding volume at 20 h postpartum was﹙207.62±65.14﹚mL， and the bleeding volume at 24 h postpartum was ﹙40.45±32.64﹚mL. The intraoperative blood loss of the control group was ﹙234.15±26.43﹚mL， 2 h postpartum hemorrhage. The amount of blood was﹙32.1±09±80.42﹚mL， and the amount of bleeding was ﹙84.12±50.07﹚mLafter birth. The amount of intraoperative blood loss， postpartum hemorrhage and postpartum 24 bleeding in the study group were significantly lower than those in the control group（t=43.258， 10.369， 7.011， P=0.001， 0.002， 0.001）. The blood transfusion and uterine strips were used in the study group. The clinical indexes of balloon use and postoperative uterine recovery were significantly better than the control group （χ2=4.682， 4.756， 4.633， 8.641， P=0.019， 0.024， 0.027， 0.033）.ConclusionHigh-risk cesarean section pregnant women with hemabate can play a good role in prevention and treatment of postpartum hemorrhage， it is worthy of clinical research and promotion.

在鄧智華[8]的研究中，將200例高危剖宮產(chǎn)孕婦分為對(duì)比組與治療組進(jìn)行研究，其中，對(duì)比組執(zhí)行縮宮素預(yù)防手段，治療組執(zhí)行欣母沛預(yù)防手段，結(jié)果顯示，治療組術(shù)中出血量（101.7±20.4）mL低于對(duì)比組（257.4±27.3）mL、產(chǎn)后2 h出血量（208.7±68.7）mL低于對(duì)比組（335.9±89.6）mL、產(chǎn)后24 h出血量（41.5±34.2）mL低于對(duì)比組（86.2±53.1）mL，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。臨床指標(biāo)對(duì)比，治療組孕婦術(shù)中術(shù)后輸血量、宮紗條或球囊使用，術(shù)后子宮恢復(fù)良好比例均明顯優(yōu)于對(duì)比組孕婦（P<0.05）。與該次研究結(jié)果高度一致，充分證實(shí)了此次研究的可信性。

綜上所述，該次研究再次論證了欣母沛藥物用于防治高危剖宮產(chǎn)孕婦產(chǎn)后出血的確切療效，利于促進(jìn)產(chǎn)婦子宮修復(fù)，臨床應(yīng)用前景可觀。

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（收稿日期：2019-08-27）