Zika virus and placenta

Beuy Joob, Viroj Wiwanitkit

1Sanitation 1 Medical Academic Center, Bangkok, Thailand

2Faculty of Medicine, University of Nis, Serbia

3Hainan Medical University, Haikou, China

4Joseph Ayobabalola University, Ikeji-Arakeji, Nigeria

5Dr DY Patil Medical University, Pune, India

Zika virus and placenta

Beuy Joob1*, Viroj Wiwanitkit2,3,4,5

1Sanitation 1 Medical Academic Center, Bangkok, Thailand

2Faculty of Medicine, University of Nis, Serbia

3Hainan Medical University, Haikou, China

4Joseph Ayobabalola University, Ikeji-Arakeji, Nigeria

5Dr DY Patil Medical University, Pune, India

ARTICLE INFO

Article history:

Received

Received in revised form Accepted

Available online

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Zika virus infection is the new arboviral infection problem. The serious outcome of infection and induction of abnormal infant become the big issue in reproductive medicine. The pathogenesis and pathology of the placenta in the affected case is an interesting issue. Here, the authors focus and discuss on this topic in this short article. Dear Editor,

Zika virus infection is a big public health problem at present. The infection in a pregnant woman might result in fetal defect. The issue on Zika virus and placenta is very interesting. As noted by Sadovsky et al., the exact pathophysiological mechanism that the virus overcomes the placenta protective mechanism is very interesting [1]. Here, we would like to try to explain the pathophysiology by view of nanoanatomy. Basically, the Zika virus’s size is about 40 nm which is considerable small. Similar to the case of HIV, the very small size of the virus can be an important factor that allows transmission of virus from mother to the fetus and further causes the problem in the fetus [2]. This can be a simple explanation for the occurrence of vertical transmission and observation on fetal defect in the pregnant infected with Zika virus. This can support the recent interesting finding that there is no direct pathology and existence of virus in the placenta in the infected cases [3].

Conflict of interest statement

We declare that we have no conflict of interest.

[1] Sadovsky Y, Clifton VL, Kn?fler M. Editorial: ZIKA virus and placenta. Placenta 2016; 40: A1.

[2] Wiwanitkit V. Re: HIV transmission from mother to child: an aspect on the placenta barrier at the nano-level. Aust N Z J Obstet Gynaecol 2005; 45(6): 539-540.

[3] Sarno M, Sacramento GA, Khouri R, do Rosário MS, Costa F, Archanjo G, et al. Zika virus infection and stillbirths: A case of hydrops fetalis, hydranencephaly and fetal demise. PLoS Negl Trop Dis 2016; 10(2): e0004517.

ment heading

10.1016/j.apjr.2016.06.006

*Corresponding author: Beuy Joob, Sanitation 1 Medical Academic Center, Bangkok Thailand.

E-mail: beuyjoob@hotmail.com