lntegrity of the hip capsule measured with magnetic resonance imaging after capsular repair or unrepaired capsulotomy in hip arthroscopy

lNTRODUCTlON

Hip arthroscopy is a more and more popular technique to address intra-articular pathology of the hip[1,2]. Entrance to the hip is made by several portals and usually an interportal or T-shaped capsulotomy is performed to improve workspace in the joint[3]. In the early days of hip arthroscopy these capsulotomies were usually left unrepaired[4]. In recent years there has been debate on what to do with the capsulotomy at the end of the procedure. Some papers suggest that routine capsular closure might result in improved outcomes after surgery where other papers report conflicting evidence and show no superiority of routine capsular repair[5-10]. However, there are cadaveric studies that show the biomechanical importance of complete capsular repair[11,12]. Restoration of the hip joint capsule results in hip joint kinematics to near normal levels after interportal or T-shaped capsulotomy[12]. The unrepaired hip capsulotomy might be a reason for developing postoperative iatrogenic hip instability[13,14]. As the (un)repaired capsulotomy might be a contributor to postoperative complaints of patients with iatrogenic hip instability, this may be quantified by assessment of the quality and morphologic appearance of the hip capsule with magnetic resonance imaging (MRI)[15].

The purpose of this study is to evaluate the integrity of the hip capsule after capsular repair or unrepaired capsulotomy measured with MRI. Our secondary aim is to evaluate the association between pre- and perioperative details and the quality and integrity of the capsule.

MATERlALS AND METHODS

Study design and participants

For the current study a random sample of 28 patients (29 hips) with residual hip complaints after surgery or complaints of the contralateral hip had an MRI scan postoperatively and were enrolled in the current study. All patients were part of a trial that was designed and approved after local medical ethical committee approval (NL55669.048.15). Inclusion criteria for the trial were age between 18-65 years, a body mass index (BMI) lower than 35 and good understanding of Dutch/English language and with intra-articular hip pathology who opt for hip arthroscopy. Exclusion criteria were revision hip arthroscopy, extra-articular hip pathology, a documented systemic connective tissue disease or hypermobility, a center-edge (CE) angle of less than 25 degrees, prior hip surgery or a hip fracture in the past. After randomization patients were either allocated to repaired capsulotomy or the unrepaired capsulotomy group. All patients were operated by the senior author. Functional outcome was measured at baseline and after 12 mo follow-up with the Copenhagen Hip and Groin Outcome Score (HAGOS)[16].

The postoperative MRI scans were independently evaluated for capsular integrity by Bech NH and Haverkamp D to assess inter observer reliability. Both authors were blinded to clinical and detailed operative information to prevent bias.

Final cohort consisted of 29 hips (28 patients) of which 16 were in the unrepaired group and 13 in the capsular repair (repair) group that had received a postoperative MRI scan.

Surgical technique

Patients were operatedstandard technique and 2 or 3 portals were made. An interportal capsulotomy was done in all patients. No T-shaped capsulotomies were done. Repair of the capsule took approximately 15 min of operating time. The capsular repair was done with 2 or 3 sutures by arthroscopic technique (Capsular Close Scorpion, Arthrex). Standard sutures were used (Fibrewire, Arthrex).

Postoperative protocol

In both groups the rehabilitation protocol was similar. The first 4 wk no weight bearing was allowed. After that, patients started weight bearing with crutches. From week 5 till week 12 patients started with passive and active exercises and were guided by a physiotherapy. After week 12 there were no more restrictions. All patients received standard 4 wk of non-steroid anti-inflammatory drugs (diclofenac) to inhibit heterotopic ossification.

Capsular quality assessment on MRI

In the paper of Weber[18] symptomatic patients were evaluated with MRI after capsular repair. They reported that 1 year after surgery 92.5% of the repaired capsules remained closed and that the capsule was thickened at the site of the repaired capsulotomy compared to the unaffected contralateral hip capsule[18].

Statistical analysis

In total there were 9 capsular defects measured on MRI, 20 hips did not have a capsular defect. For the assessment of the presence of capsular defect there was 100% agreement between observers. In the repair group, there were 2 patients (15.4%) with a measurable capsular defect on MRI, and in the unrepaired group 7 patients (43.8%) (= 0.13).

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Analysis was performed by use of SPSS statistical software (IBM Corp. IBM SPSS Statistics for Macintosh Version 26.0. Armonk, NY: IBM Corp).

RESULTS

Patient demographics

The mean age in the unrepaired group was 33.3 ± 6.1 and in the repair group 31.4 ± 9.1. Average followup in the repair group was 15.8 ± 6.5 mo and in the unrepaired group 12.6 ± 6.7 mo. Regarding baseline characteristics there were no significant differences between both groups (Table 1).

Regarding the HAGOS functional outcome score both baseline and 12 mo follow-up values are given in Table 2. In the capsule defect group, 7 patients reached the 12 mo follow-up, in the capsule intact group, 16 patients reached the 12 mo follow-up. Between the capsule intact and the capsular defect group, there were no differences on all 5 domains of the HAGOS outcome score (Table 2).

Capsular defects

Patient and clinical characteristics are described as means ± SD in case of normally distributed continuous variables. Otherwise, medians with ranges are presented. Comparisons between repair groups were performed by use of-tests or non-parametric Mann Whitney-tests where appropriate. Categorical variables are presented as numbers with accompanying proportions and analyzed by use oftests or Fischer Exact-tests (in case of expected numbers ＜ 5). For the presence of a capsular gap, absolute agreement was calculated to present inter observer reliability. The association between pre- and perioperative details and the presence of a defect was analyzed by use of a univariate logistic regression analysis and Odds ratios (OR) with 95%CI were calculated. Intra class correlation coefficients (ICC, 2-way random effect model) were calculated for both acetabular and muscular gap length. Avalue ＜ 0.05 was considered statistically significant.

In the capsular repair group, there were 2 failures. The first was a 23-year-old woman with a large CE angle (44 degrees) and a BMI of 24,6. The second patient was a 45-year-old woman with a hip that had already some signs of osteoarthritis, a CE angle of 36.9 degrees and a BMI of 33.3.

A random sample of patients were enrolled in this case series. All were operated and had a magnetic resonance imaging (MRI) scan in the postoperative phase. Patients were part of an earlier performed randomized trial and were randomized into a capsular repair or unrepaired capsulotomy group. Outcome was the presence of a capsular defect on MRI and the Copenhagen Hip and Groin Outcome Score (HAGOS).

Gap size

Inter observer reliability of gap size measurements was good to excellent with ICC values of 0.83 and 0.94 of the gap measurements at the acetabular and muscular side.

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Among patients with a capsular defect, median gap sizes at the acetabular side were 5.9 mm (range: 2.7-9.0) and 8.0 mm (range: 4.5-18.0) in the repaired and unrepaired group, respectively (= 0.462). At the muscular side, gap sizes were 6.6 mm (range: 4.1-9.0) and 11.5 mm (range: 3.0-18.0), respectively (= 0.857).

Clinical characteristics and capsular defect

Although not significant patients with a larger CE angle were more likely to have a capsular defect on MRI with an OR of 1.12 (= 0.06).

In the group of patients with a capsular defect, there were 2 with a CAM-type deformity and 5 with a pincer-type deformity. In the capsule intact group, there were 6 patients with a CAM-type deformity and 9 patients with a pincer-type deformity. There was no significant association between the presence of a CAM or pincer deformity and a capsular defect (Table 3).

In the capsular defect group, there was 1 patient that underwent a labral repair; in the capsule intact group, 11 patients underwent a labral repair. Patients with a labral repair were less likely to have a capsular defect on MRI with an OR of 0.1 compared to patients without labral repair (= 0.05) (Table 3).

More studies are needed to determine what the effect is of capsular repair on capsular healing after hip arthroscopy.

DlSCUSSlON

In this case series we found that the incidence of a capsular defect, although not significant, was higher in the unrepaired capsulotomy group than in the repaired group. Our results are comparable to available current literature. In the randomized controlled trial of Strickland[17] they investigated 30 hips and compared capsular closureunrepaired interportal capsulotomy during simultaneous bilateral arthroscopy. They measured the capsular defect and the quality of the capsule postoperatively and report no significant differences between treatment groups at final endpoint at 24 wk after surgery. Kraeutler[19] performed a multicenter randomized trial between capsular repair and unrepaired capsulotomy. They also report no differences between both treatment groups regarding healing of the capsule measured on MRI[19].

The used technique for measuring capsular defects has been previously described in the paper of Strickland[17]. Capsular integrity was measured on a proton weighted density sequence or the T2 weighted fat-saturated sequence in the coronal plane. First step was to determine if there was a capsular defect (Figure 1). The definition of a capsular defect was described by Weber[18]; being any visual disruption of the iliofemoral ligament or any appearance of communication between the joint and the iliofemoral bursa seen with contrast (Figure 1A and B)[18]. Furthermore, we measured 2 parameters: Gap length on the acetabular side and the gap length on the muscular side of the defect (Figure 1A and B)

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To our best knowledge there is no literature that investigated the association between the size of the CE-angle and the presence of a capsular defect. In our series the likelihood of a capsular defect was larger with an increasing CE angle. An explanation for this finding could be that in this group the incidence of pincer impingement was higher. As part of the procedure of pincer impingement the surgeon must resect a part of the acetabulum and detach a part of the iliofemoral ligament. Extended resection and concomitant ligament damage could lead to possible higher incidence of capsular defects after surgery. In our series there were only 2 failures in the capsular repair group that showed a capsular defect on MRI. Possibly the rather large CE angle in both patients was of influence and led to subsequent failure of capsular healing.

Regarding labral repair there was a significant larger portion of patients with an intact capsule in the labral repair group. It is unsure where the difference in capsular defects between labral repair and no repair originates from. A possibility is that more stability from a repaired labrum influences the capsular healing. Cadaveric studies show that an intact labrum absorbs a lot of strain during motion of the hip[20]. Without the intact labrum the hip capsule might have to compensate for these forces resulting in possibly a higher incidence of capsular defects.

Strengths

A strength of this study is that the capsular defect was measured by two authors separately and that an intra classifier coefficient was calculated to verify the accuracy of the measured defects.

Limitations

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CONCLUSlON

Our current study shows that there is no significant difference in capsular healing on MRI between capsular repair or unrepaired capsulotomy. Furthermore, a higher CE angle increases the likelihood of having a capsular defect and the presence of a labral repair decreases the likelihood of a capsular defect. Although there seems to be no reason for routinely capsular closure after hip arthroscopy, knowing these patient specific factors might help the orthopedic surgeon to decide to perform a capsular repair in specific cases.

ARTlCLE HlGHLlGHTS

Research background

Capsular management after hip arthroscopy remains topic of debate after an interportal capsulotomy

Research motivation

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Research objectives

To determine whether capsular repair or not may result in a capsular defect measured on an MRI scan.Secondary objective is to determine of the presence of a capsular defect might influence the clinical outcome after hip arthroscopy.

The first limitation of this study is that small number of patients were included. We expect that although there was a clinically relevant difference in measurable defect between the groups, this difference was not statistically different because of the small sample size. Secondly, only symptomatic patients or patients with complaints of the contralateral hip had an MRI scan and this could have introduced a bias in our results.

Research methods

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Research results

A total of 29 hips were included. There was no significant different number of capsular defects between the capsular repair or unrepaired capsulotomy groups. There was also no difference in outcome measured with HAGOS outcome score between the capsular defect or capsule intact group.

Research conclusions

There was no difference in the number of capsular defects between the capsular repair or unrepaired capsulotomy group.

Research perspectives

Future larger studies are needed to confirm that capsular repair or unrepaired capsulotomy has no influence on the presence of a capsular defect or not. In addition; long term analysis needs to be done to determine whether the presence of a capsular defect might result in long term complications or influence outcome.

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Bech NH drafted the manuscript, was involved with data collection, and assisted with data analysis; van Dijk LA drafted the manuscript and participated in design of the study; de Waard S was involved with data collection, and assisted with data analysis; Vuurberg G drafted the manuscript, and assisted with data analysis; Sierevelt IN participated in study design and performed statistical analysis; Kerkhoffs GM participated in study design; Haverkamp D participated in design of the study drafted the manuscript and was involved with data collection; and all authors read and approved the final manuscript.

This study was part of an earlier performed randomized controlled trial. This trial was approved by the local medical ethical committee and was registered at the CCMO Dutch Trial Register: NL55669.048.15.

All study participants, or their legal guardian, provided informed written consent prior to study enrollment.

All authors declare that there is no conflict of interest.

No additional data are available.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BYNC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Netherlands

Niels H Bech 0000-0002-7772-2410; Lode A van Dijk 0000-0001-6599-3654; Sheryl de Waard 0000-0002-2271-806X; Gwendolyn Vuurberg 0000-0001-5008-890X; Inger N Sierevelt 0000-0003-0924-9358; Gino MMJ Kerkhoffs 0000-0001-7910-7123; Dani?l Haverkamp 0000-0001-7360-9763.

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Wang JL

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Wang JL