短波紫外線治療小兒皰疹性口腔炎的療效和安全性

劉麗艷 李繼安 聶秀真 王少寧 林愛偉

[摘要] 目的 探討短波紫外線治療小兒皰疹性口腔炎的療效和安全性。 方法 選取2019年1月至2020年5月期間入住我院的皰疹性口腔炎患兒112例為研究對象，隨機分為對照組與試驗組，每組各56例。對照組給予抗病毒、口腔護理和維持水電解質(zhì)平衡等常規(guī)治療，試驗組在對照組治療基礎上加用短波紫外線口腔局部照射，每天1次，每次4～6 s，連用5 d。比較兩組患兒的總有效率、熱退時間、食欲改善時間、皰疹消失時間及潰瘍發(fā)生率。觀察短波紫外線口腔局部照射的副反應。 結果 試驗組患兒的熱退時間、食欲改善時間及口腔皰疹消退時間均明顯短于對照組，差異有統(tǒng)計學意義（P<0.05）。試驗組口腔潰瘍發(fā)生率明顯低于對照組，差異有統(tǒng)計學意義（P<0.05）。試驗組治療總有效率為92.9%，對照組為78.6%，試驗組明顯高于對照組，差異有統(tǒng)計學意義（P<0.05）。短波紫外線治療口腔皰疹及潰瘍無不適和疼痛，未發(fā)現(xiàn)明顯副作用。 結論 藥物配合短波紫外線局部照射治療小兒皰疹性口腔炎安全、有效。

[關鍵詞] 短波紫外線;治療;小兒;皰疹性口腔炎;療效;副作用

[中圖分類號] R725.1? ? ? ? ? [文獻標識碼] B? ? ? ? ? [文章編號] 1673-9701（2021）24-0082-04

Efficacy and safety of shortwave ultraviolet in the treatment of herpetic stomatitis in children

LU Liyan? ?LI Ji′an? ?NIE Xiuzhen? ?WANG Shaoning? ?LIN Aiwei

Department of Infectious Diseases， Ji′nan Children′s Hospital， Ji′nan? ?250022， China

[Abstract] Objective To explore the efficacy and safety of shortwave ultraviolet in the treatment of herpetic stomatitis in children. Methods A total of 112 children with herpetic stomatitis who were admitted to our hospital from January 2019 to May 2020 were selected as the research subjects，and they were randomly divided into the control group and the experimental group，with 56 cases in each group. The control group was given conventional treatments such as antiviral，oral care，and maintaining water and electrolyte balance.The experimental group was given shortwave ultraviolet local oral irradiation on the basis of the control treatment， once a day， 4-6 seconds each time， five days in a row. The total effective rate， the antipyretic time， the time of appetite improvement， the time of herpes disappearance， and the incidence of ulcers were compared between the two groups. The side effects of local shortwave ultraviolet radiation in the oral cavity were observed. Results The antipyretic time， appetite improvement time， and oral herpes subsidence time of the children in the experimental group were significantly shorter than those of the control group， and the difference was statistically significant（P<0.05）. The incidence of oral ulcers in the experimental group was significantly lower than that in the control group， and the difference was also statistically significant （P<0.05）. The total effective rate of treatment in the experimental group was 92.9%， and the total effective rate in the control group was 78.6%. The total effective rate of the experimental group was significantly higher than that of the control group， and the difference was statistically significant（P<0.05）. There was no discomfort and pain in the treatment of oral herpes and ulcers with shortwave ultraviolet rays， and no obvious side effects were found. Conclusion Drugs combined with shortwave ultraviolet local irradiation are safe and effective in the treatment of herpetic stomatitis in children.